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Your Position: Casa > Protein > CCL23 > CC3-H5244

Human CCL23 Protein, His Tag (MALS verified)

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  • Synonym
    CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23, hmrp-2a
  • Source
    Human CCL23 Protein, His Tag(CC3-H5244) is expressed from human 293 cells (HEK293). It contains AA Arg 22 - Asn 120 (Accession # P55773-1).
    Predicted N-terminus: His
  • Molecular Characterization
    CCL23 Structure

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 13.3 kDa. The protein migrates as 12-17 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
CCL23 SDS-PAGE

Human CCL23 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
CCL23 MALS images

The purity of Human CCL23 Protein, His Tag (Cat. No. CC3-H5244) is more than 90% and the molecular weight of this protein is around 15-21 kDa verified by SEC-MALS.

Bioactivity-ELISA
 CCL23 ELISA

Immobilized Human CCL23 Protein, His Tag (Cat. No. CC3-H5244) at 5 μg/mL (100 μL/well) can bind Heparin Biotin with a linear range of 0.078-2.5 μg/mL (QC tested).

  • Background
    This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.
  • Clinical and Translational Updates

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Price(EUR) : €350.00

Price(EUR) : €2330.00

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