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Your Position: Casa > Protein > DR6 > TN1-H5252

Human DR6 / TNFRSF21 Protein, Fc Tag

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  • Sinónimo
    TNFRSF21,DR6,CD358,BM-018
  • Fuente
    Human DR6, Fc Tag (TN1-H5252) is expressed from human 293 cells (HEK293). It contains AA Gln 42 - Leu 350 (Accession # AAH17730).
    Predicted N-terminus: Gln 42
  • Caracterización molecular
    Online(Gln 42 - Leu 350) AAH17730

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 60.2 kDa. The protein migrates as 80-95kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxina
    Less than 1.0 EU per μg by the LAL method.
  • Pureza

    >90% as determined by SDS-PAGE.

  • Formulación

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitución

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Almacenamiento

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human DR6, Fc Tag (Cat. No. TN1-H5252) SDS-PAGE gel

Human DR6, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • Antecedentes
    Tumor necrosis factor receptor superfamily member 21 (TNFRSF21) is also known as death receptor 6 (DR6), which is a member of the TNF-receptor superfamily. TNFRSF21 contains one death domain and four TNFR-Cys repeats. TNFRSF21 / DR6 has been shown to activate NF-κB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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ETA de productos en stock: 2 días laborables

Price(EUR) : €290.00

Price(EUR) : €1330.00

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