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Your Position: Casa > Protein > OX40 > OX0-R5253

Rat OX40 / TNFRSF4 / CD134 Protein, Fc Tag

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  • Synonym
    TNFRSF4,OX40,CD134,OX40L receptor,ACT35,TXGP1L
  • Source
    Rat OX40, Fc Tag(OX0-R5253) is expressed from human 293 cells (HEK293). It contains AA Val 20 - Pro 210 (Accession # P15725).
    Predicted N-terminus: Val 20
  • Molecular Characterization
    OX40 Structure

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 47.7 kDa. The protein migrates as 66 kDa under reducing (R) condition, and 150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
OX40 SDS-PAGE

Rat OX40, Fc Tag on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity-ELISA
 OX40 ELISA

Immobilized Rat OX40, Fc Tag (Cat. No. OX0-R5253) at 2 μg/mL (100 μL/well) can bind Rat OX40 Ligand, His Tag (Cat. No. OXL-R5248) with a linear range of 10-78 ng/mL (Routinely tested).

 OX40 ELISA

Immobilized Rat OX40 Ligand, His Tag (Cat. No. OXL-R5248) at 2 μg/mL (100 μL/well) can bind Rat OX40, Fc Tag (Cat. No. OX0-R5253) with a linear range of 0.1-1 ng/mL (Routinely tested).

  • Background
    Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.
  • Clinical and Translational Updates

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ETA de productos en stock: 2 días laborables

Price(EUR) : €320.00

Price(EUR) : €2060.00

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  • Number of Drugs in Clinical Trials:26 Details
  • Latest Research Phase:Phase 3 Clinical

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