Acrobiosystems for English
icon_bulk_orderConsulta masiva/Pedido rápido
user
  1. Cuadro de mandos
  2. Mi perfil
  3. Mi dirección
  4. Mis pedidos
  5. Afiliación a Acro
Iniciar sesión Registro
Promotion
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2
0
No hay productos en el carro de la compra
Mi carro|Check Out
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Casa > M-CSF

M-CSF

Brief Information

Name:Macrophage Colony Stimulating Factor 1
Target Synonym:M-CSF,Macrophage colony-stimulating factor 1,CSF-1,CSF1,Colony Stimulating Factor 1,Colony Stimulating Factor 1 (Macrophage),Macrophage Colony Stimulating Factor 1,Lanimostim,MCSF,Macrophage Colony-Stimulating Factor,MGC31930
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

Product ListCompare or Buy

Product> Filter Results
Por estado del producto :
Por categoría de producto :
Por especies :
Por etiqueta :
Por Conjugado::
Cat. No. Especies Descripción del producto Estructura Pureza Característica
GMP-MCFH24 Human GMP Human M-CSF Protein
GMP-MCFH24-structure
MCF-H5218 Human Human M-CSF / CSF-1 Protein, premium grade
MCF-H5218-structure
MCF-H5218-sds
MCF-H82E6 Human Biotinylated Human M-CSF / CSF-1 Protein, His,Avitag™
MCF-H82E6-structure
MCF-H82E6-sds
MCF-H5247 Human Human M-CSF / CSF-1 Protein, His Tag
MCF-H5247-structure
MCF-H5247-sds
ACRO Quality

Part of Bioactivity data

MCF-H5218-Cell-based assay
M-CSF CELL

Human M-CSF Protein, premium grade (Cat. No. MCF-H5218) stimulates proliferation of M-NFS-60 cells. The specific activity of Human M-CSF Protein, premium grade is＞6.00 x 10^7 IU/mg, which is calibrated against WHO International Standard (NIBSC code: 89/512) (QC tested).

Protocol
MCF-H82E6-Cell-based assay
M-CSF CELL

Biotinylated Human M-CSF, His,Avitag (Cat. No. MCF-H82E6) stimulates proliferation of RAW264.7 cells. The EC50 for this effect is 6.20-7.15 ng/mL (Routinely tested).

Protocol
MCF-H82E6-SPR
M-CSF SPR

Biotinylated Human M-CSF, His,Avitag (Cat. No. MCF-H82E6) immobilized on SA Chip can bind Human M-CSF R, His Tag (Cat. No. CSR-H5228) with an affinity constant of 0.309 μM as determined in a SPR assay (Biacore T200) (Routinely tested).

Protocol
MCF-H5247-SPR
M-CSF SPR

Human M-CSF, His Tag (Cat. No. MCF-H5247) captured on CM5 Chip via anti-His antibody can bind Human M-CSF R, Fc Tag, low endotoxin (Cat. No. CSR-H5258) with an affinity constant of 1.9 nM as determined in SPR assay (Biacore T200) (Routinely tested).

Protocol

Synonym Name

M-CSF,CSF-1,Lanimostim

Background

The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. It is one of the three experimentally described colony-stimulating factors. M-CSF binds to the colony stimulating factor 1 receptor. Macrophage colony-stimulating factor has been shown to interact with PIK3R2. M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. Locally produced M-CSF in the vessel wall contributes to the development and progression of atherosclerosis.

Clinical and Translational Updates

Related Molecule

M-CSF R

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Lacnotuzumab MCS-110 Phase 2 Clinical Novartis Pharma Ag Bone metastases; Giant Cell Tumor of Tendon Sheath; Stomach Neoplasms; Synovitis, Pigmented Villonodular; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Breast Neoplasms; Giant Cell Tumors; Endometrial Neoplasms; Melanoma Details
Lacnotuzumab MCS-110 Phase 2 Clinical Novartis Pharma Ag Bone metastases; Giant Cell Tumor of Tendon Sheath; Stomach Neoplasms; Synovitis, Pigmented Villonodular; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Breast Neoplasms; Giant Cell Tumors; Endometrial Neoplasms; Melanoma Details

This web search service is supported by Google Inc.

totop
Call us
Call us

Germany+49 800 0826645

United Kingdom+44 808 281 3436

Netherlands+31 800 0224992

Switzerland+41 800 040 012

France+33 800 90 78 85

Sweden+46 20 12 76 94

Denmark+45 80 83 07 62

Belgium+32 800 27 125

Email
Correo electrónico
order@acrobiosystems.com
Fax
Fax
+1 888-377-6111
Address
Address
Lichtstrasse 35,4056 Basel, Switzerland
linkedin twitter facebook youtube

Dejar un mensaje

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap