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BMP-4

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Cat. No. Especies Descripción del producto Estructura Pureza Característica
BM4-H5118 Human Human BMP-4 / BMP2B (improved sequence) Protein, premium grade
BM4-H5118-sds
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Part of Bioactivity data

BM4-H5118-Cell-based assay
BMP-4 CELL

Human BMP-4 (improved sequence) Protein, premium grade (Cat. No. BM4-H5118) stimulates Human BMP (Luc) HEK293 Reporter cell (pool). The EC50 value of this effect is 0.094 μg/mL (Routinely tested).

Protocol

Synonym Name

BMP4,BMP2B,BMP2B1,MCOPS6,OFC11,ZYME

Background

Bone Morphogenetic Protein 4 (BMP4) is a member of growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. BMP-4 Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. BMP-4 can acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction.

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