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Your Position: Casa > GRIN2B

GRIN2B

Brief Information

Name:Glutamate [NMDA] receptor subunit epsilon 2
Target Synonym:NR2B,hNR3,GluN2B,NMDAR2B,NR3,GRIN2B,Glutamate Ionotropic Receptor NMDA Type Subunit 2B,Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B,Glutamate [NMDA] Receptor Subunit Epsilon-2,N-Methyl D-Aspartate Receptor Subtype 2B,N-Methyl-D-Aspartate Receptor Subunit 3,Glutamate Receptor Subunit Epsilon-2,EIEE27,MRD6,Glutamate Receptor Ionotropic, NMDA 2B
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:7
Lastest Research Phase:Phase 3 Clinical

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ACRO Quality

Synonym Name

NMDAR2B

Background

NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family that mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation.

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