Acrobiosystems for English
icon_bulk_orderConsulta masiva/Pedido rápido
user
  1. Cuadro de mandos
  2. Mi perfil
  3. Mi dirección
  4. Mis pedidos
  5. Afiliación a Acro
Iniciar sesión Registro
Promotion
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2
0
No hay productos en el carro de la compra
Mi carro|Check Out
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Casa > Angiogenin

Angiogenin

Brief Information

Name:Cleavage and polyadenylation specificity factor subunit 3
Target Synonym:YSH1,Cleavage And Polyadenylation Specificity Factor 73 KDa Subunit,Cleavage And Polyadenylation Specific Factor 3, 73kD Subunit,CPSF 73 KDa Subunit,NEDMHSN,NEDMHS,EC 3.1.27,Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit),mRNA 3 -end-processing endonuclease CPSF-73,CPSF73,Cleavage And Polyadenylation Specific Factor 3,CPSF-73,Cleavage And Polyadenylation Specificity Factor Subunit 3,Cleavage And Polyadenylation Specific Factor 3, 73kDa,MRNA 3 -End-Processing
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 1 Clinical

Product ListCompare or Buy

Product> Filter Results
Por estado del producto :
Por categoría de producto :
Por especies :
Por etiqueta :
Por Conjugado::
Cat. No. Especies Descripción del producto Estructura Pureza Característica
ANN-H5149 Human Human Angiogenin / RNASE5 Protein, His Tag
ANN-H5149-structure
ANN-H5149-sds
ACRO Quality

Part of Bioactivity data

ANN-H5149-ELISA
Angiogenin SPR

Human Angiogenin, His Tag (Cat. No. ANN-H5149) immobilized on CM5 Chip can bind Human Plexin B2, His Tag (Cat. No. PL2-H52H3) with an affinity constant of 17.5 nM as determined in a SPR assay (Biacore 8K) (QC tested).

Protocol

Synonym Name

ALS9,ANG,Angiogenin,angiogenin, ribonuclease, RNase A family, 5,EC 3.1.27,EC:3.1.27.-

Background

Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
DNDI-6148 DNDI-6148 Phase 1 Clinical Drugs For Neglected Diseases Initiative Infections; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral Details
AN-3661 AN-6426; AN-3661 Phase 1 Clinical Anacor Pharmaceuticals Inc Malaria Details
DNDI-6148 DNDI-6148 Phase 1 Clinical Drugs For Neglected Diseases Initiative Infections; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral Details
AN-3661 AN-6426; AN-3661 Phase 1 Clinical Anacor Pharmaceuticals Inc Malaria Details

This web search service is supported by Google Inc.

totop
Call us
Call us

Germany+49 800 0826645

United Kingdom+44 808 281 3436

Netherlands+31 800 0224992

Switzerland+41 800 040 012

France+33 800 90 78 85

Sweden+46 20 12 76 94

Denmark+45 80 83 07 62

Belgium+32 800 27 125

Email
Correo electrónico
order@acrobiosystems.com
Fax
Fax
+1 888-377-6111
Address
Address
Lichtstrasse 35,4056 Basel, Switzerland
linkedin twitter facebook youtube

Dejar un mensaje

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap