Acrobiosystems for English
icon_bulk_orderConsulta masiva/Pedido rápido
user
  1. Cuadro de mandos
  2. Mi perfil
  3. Mi dirección
  4. Mis pedidos
  5. Afiliación a Acro
Iniciar sesión Registro
Promotion
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2
0
No hay productos en el carro de la compra
Mi carro|Check Out
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Casa > STEAP1

STEAP1

Brief Information

Name:Six-transmembrane epithelial antigen of the prostate 1
Target Synonym:PRSS24,Six-transmembrane epithelial antigen of prostate 1,STEAP,STEAP1,STEAP Family Member 1,Six Transmembrane Epithelial Antigen Of The Prostate 1,STEAP1 Metalloreductase,Six Transmembrane Epithelial Antigen Of The Prostate,Metalloreductase STEAP1,EC 1.16.1.-,EC:1.16.1.-
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Phase 2 Clinical

Product ListCompare or Buy

Product> Filter Results
Por estado del producto :
Por categoría de producto :
Por especies :
Por etiqueta :
Por Conjugado::
Cat. No. Especies Descripción del producto Estructura Pureza Característica
CHEK-ATP154 Human HEK293/Human STEAP1 Stable Cell Line
ST1-H5283 Human Human STEAP1 Full Length Protein, Twin-Strep,His Tag (Detergent)
ST1-H5283-structure
ST1-H5283-sds
SCCHO-ATP121 Human CHO/Human STEAP1 Stable Cell Line Development Service
ACRO Quality

Part of Bioactivity data

CHEK-ATP154-Cell-based assay
STEAP1 FACS

Fig. FACS analysis of STEAP1 on HEK293/Human STEAP1 Stable Cell Line.
FACS assay shows that Anti-STEAP1 antibody can bind to HEK293/Human STEAP1 Stable Cell Line. HEK293/Human STEAP1 Stable Cell Line was red line, Negative control HEK293 cells was grey line(QC tested).

Protocol
SCCHO-ATP121-Cell-based assay
STEAP1 FACS

Expression analysis of human STEAP1 on CHO/Human STEAP1 Stable Cell Line by FACS.
Cell surface staining was performed on CHO/Human STEAP1 Stable Cell Line or negative control cell using anti-human STEAP1 antibody followed by staining with PE anti-human IgG Fc Antibody.

Protocol
ST1-H5283-SPR
STEAP1 SPR

Anti-STEAP1 Antibody captured on Protein A Chip can bind Human STEAP1 Full Length Protein, Twin-Strep,His Tag (Cat. No. ST1-H5283) with an affinity constant of 2.95 nM as determined in a SPR assay (in presence of DDM and CHS) (Biacore 8K) (Routinely tested).

Protocol
ST1-H5283-ELISA
STEAP1 ELISA

Immobilized Human STEAP1 Full Length Protein, Twin-Strep,His Tag (Cat. No. ST1-H5283) at 5 μg/mL (100 μL/well) on a Nickel Coated plate can bind Anti-STEAP1 Antibody with a linear range of 0.156-2.5 μg/mL (QC tested).

Protocol

Synonym Name

STEAP1, PRSS24, STEAP

Background

Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III). Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
89Zr-DFO-MSTP2109A Phase 2 Clinical Memorial Sloan Kettering Cancer Center, Genentech Inc Prostatic Neoplasms Details
STEAP1 CART Cell Therapy(PromiCell) Phase 2 Clinical PromiCell Therapeutics Inc, Fred Hutchinson Cancer Research Center Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms Details
Xaluritamig AMG-509 Phase 1 Clinical Xencor Inc, Amgen Inc Prostatic Neoplasms, Castration-Resistant Details
ABBV-969 ABBV-969; ABBV969 Phase 1 Clinical Abbvie Inc, Immunogen Inc Prostatic Neoplasms, Castration-Resistant Details
89Zr-DFO-MSTP2109A Phase 2 Clinical Memorial Sloan Kettering Cancer Center, Genentech Inc Prostatic Neoplasms Details
STEAP1 CART Cell Therapy(PromiCell) Phase 2 Clinical PromiCell Therapeutics Inc, Fred Hutchinson Cancer Research Center Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms Details
Xaluritamig AMG-509 Phase 1 Clinical Xencor Inc, Amgen Inc Prostatic Neoplasms, Castration-Resistant Details
ABBV-969 ABBV-969; ABBV969 Phase 1 Clinical Abbvie Inc, Immunogen Inc Prostatic Neoplasms, Castration-Resistant Details

This web search service is supported by Google Inc.

totop
Call us
Call us

Germany+49 800 0826645

United Kingdom+44 808 281 3436

Netherlands+31 800 0224992

Switzerland+41 800 040 012

France+33 800 90 78 85

Sweden+46 20 12 76 94

Denmark+45 80 83 07 62

Belgium+32 800 27 125

Email
Correo electrónico
order@acrobiosystems.com
Fax
Fax
+1 888-377-6111
Address
Address
Lichtstrasse 35,4056 Basel, Switzerland
linkedin twitter facebook youtube

Dejar un mensaje

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap