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| Cat. No. | Especies | Descripción del producto | Estructura | Pureza | Característica |
|---|---|---|---|---|---|
| GD8-M5243 | Mouse | Mouse latent GDF-8 Protein, His Tag |  |
|
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| GD8-M82Q3 | Mouse | Biotinylated Mouse latent GDF-8 Protein, Avitag™,His Tag |  |
|
|
| GD8-H82Q3 | Human | Biotinylated Human Latent GDF-8 Protein, His,Avitag™ |  |
|
|
| GD8-H8243 | Human | Biotinylated Human latent GDF-8 Protein, His Tag, ultra sensitivity (primary amine labeling) (MALS & SPR verified) |  |
|
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| GD8-H5343 | Human | Human Latent GDF-8 Protein, His Tag | |||
| GD8-H5243 | Human | Human latent GDF-8 Protein, His Tag (MALS verified) |  |
|
Human Follistatin Protein, His Tag, premium grade (Cat. No. FON-H52H4) immobilized on CM5 Chip can bind Biotinylated Human latent GDF-8 Protein, His Tag (Cat. No. GD8-H8243) with an affinity constant of 248 nM as determined in a SPR assay (Biacore 8K) (QC tested).
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Talditercept alfa | RO-7239361; BMS-986089; RG-6206; BHV-2000 | Phase 3 Clinical | Bristol-Myers Squibb Company | Muscular Dystrophy, Duchenne; Neuromuscular Diseases; Muscular Atrophy, Spinal | Details |
| Apitegromab | SRK-015 | Phase 3 Clinical | Scholar Rock | Spinal Muscular Atrophies of Childhood; Neuromuscular Manifestations; Muscular Atrophy; Neuromuscular Diseases; Muscular Atrophy, Spinal; Atrophy | Details |
| RO-7204239 | GYM-329; RO-7204239; RG-6237; RG-70240 | Phase 3 Clinical | F. Hoffmann-La Roche Ltd, Chugai Pharmaceutical Co Ltd | Muscular Dystrophy, Facioscapulohumeral; Muscular Atrophy, Spinal | Details |
| Trevogrumab | REGN-1033; REGN1033; SAR-391786; GDF8 | Phase 2 Clinical | Myositis, Inclusion Body; Obesity; Sarcopenia | Details | |
| AAV1-FS344 | AAV1-Follistatin; AAV1-FS344 | Phase 2 Clinical | Nationwide Children'S Hospital | Becker muscular dystrophy; Myositis, Inclusion Body; Muscular Dystrophy, Duchenne | Details |
| ACE-2494 | ACE-2494 | Phase 1 Clinical | Acceleron Pharma Inc | Details | |
| KER-065 | KER-065; RKER-065 | Phase 1 Clinical | Keros Therapeutics Inc | Neuromuscular Diseases; Obesity | Details |
| Talditercept alfa | RO-7239361; BMS-986089; RG-6206; BHV-2000 | Phase 3 Clinical | Bristol-Myers Squibb Company | Muscular Dystrophy, Duchenne; Neuromuscular Diseases; Muscular Atrophy, Spinal | Details |
| Apitegromab | SRK-015 | Phase 3 Clinical | Scholar Rock | Spinal Muscular Atrophies of Childhood; Neuromuscular Manifestations; Muscular Atrophy; Neuromuscular Diseases; Muscular Atrophy, Spinal; Atrophy | Details |
| RO-7204239 | GYM-329; RO-7204239; RG-6237; RG-70240 | Phase 3 Clinical | F. Hoffmann-La Roche Ltd, Chugai Pharmaceutical Co Ltd | Muscular Dystrophy, Facioscapulohumeral; Muscular Atrophy, Spinal | Details |
| Trevogrumab | REGN-1033; REGN1033; SAR-391786; GDF8 | Phase 2 Clinical | Myositis, Inclusion Body; Obesity; Sarcopenia | Details | |
| AAV1-FS344 | AAV1-Follistatin; AAV1-FS344 | Phase 2 Clinical | Nationwide Children'S Hospital | Becker muscular dystrophy; Myositis, Inclusion Body; Muscular Dystrophy, Duchenne | Details |
| ACE-2494 | ACE-2494 | Phase 1 Clinical | Acceleron Pharma Inc | Details | |
| KER-065 | KER-065; RKER-065 | Phase 1 Clinical | Keros Therapeutics Inc | Neuromuscular Diseases; Obesity | Details |
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