0
No hay productos en el carro de la compra
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Casa > Protein > 4-1BB Ligand > 41L-R52D3

Rat 4-1BB Ligand / TNFSF9 Protein, His,Flag Tag (MALS verified)

Order Now

  • Synonym
    4-1BB Ligand,TNFSF9,CD137L
  • Source
    Rat 4-1BB Ligand His,Flag Tag(41L-R52D3) is expressed from human 293 cells (HEK293). It contains AA Pro 106 - Gly 308 (Accession # Q80WE6-1).
    Predicted N-terminus: His
  • Molecular Characterization
    4-1BB Ligand Structure

    This protein carries a polyhistidine tag at the N-terminus, followed by a flag tag

    The protein has a calculated MW of 72.3 kDa. The protein migrates as 95-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
4-1BB Ligand SDS-PAGE

Rat 4-1BB Ligand His,Flag Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
4-1BB Ligand MALS images

The purity of Rat 4-1BB Ligand His,Flag Tag (Cat. No. 41L-R52D3) is more than 90% and the molecular weight of this protein is around 169-206 kDa verified by SEC-MALS.

Bioactivity-ELISA
 4-1BB Ligand ELISA

Immobilized Mouse 4-1BB, Fc Tag (Cat. No. 41B-M5258) at 1 μg/mL (100 μL/well) can bind Rat 4-1BB Ligand His,Flag Tag (Cat. No. 41L-R52D3) with a linear range of 5-39 ng/mL (QC tested).

  • Background
    Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
  • Clinical and Translational Updates

Comments (0)


ETA de productos en stock: 2 días laborables

Price(EUR) : €350.00

Price(EUR) : €2570.00

Promotion & Exhibitions



Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:2 Details
  • Latest Research Phase:Phase 2 Clinical

Datasheet & Documentation

Request for DMF
DMF (Drug Master File)

Related Products

New Product Launch

Questions & Comments

This web search service is supported by Google Inc.

totop
Email
Correo electrónico
Fax
Fax
+1 888-377-6111
Address
Address
Lichtstrasse 35,4056 Basel, Switzerland

Dejar un mensaje