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Fluorescent Human SSTR2 Full Length Protein (VLP)

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Cat. No. / Size
Price
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SS2-HF2G3-20ug
$620.00
SS2-HF2G3-100ug
$1235.00
SS2-HF2G3-500ug (250ug X 2)
$4305.00
ETA of in-stock products:2 business days
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Product Details

  • Application

    1. Immunization
    2. Cell based assay (FACS or functional assay)
    3. Screening (ELISA)
  • Synonyms

    Smstr2, Somatostatin R2, somatostatin receptor 2, somatostatin receptor type 2, SomatostatinR2, SRIF-1, SS2R, SS-2-R, SS2-R, SST2, SSTR2

  • Source

    Fluorescent Human SSTR2 Full Length Protein (VLP) (SS2-HF2G3) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ile 369 (Accession # P30874-1).

    Predicted N-terminus: Asp

  • Molecular Characterization

    This protein carries a GFP tag.

    *The isotype control of empty/mock VLP (Cat. No. VLP-NF2P4) is sold separately and not included in protein, you can follow the link for product information.

    1. Structure

      Virus-like particles (VLPs) are protein particles that mimic the shape of viruses but lack a viral genome, and incorporating transmembrane proteins on the external surface.

    2. Synthesis Process

      Envelope virus-like particles (eVLPs) are produced by co-expressing target membrane proteins with viral structural proteins in mammalian cells, enabling native embedding of membrane proteins into the lipid bilayer during VLP budding. This approach preserves authentic conformation, post-translational modifications, and orientation, while creating a completely detergent-free environment with repetitive multivalent display and strong immunogenicity making them ideal for immunization, binding assays in antibody discovery and screening (ELISA), and cell-based assays such as FACS, etc.

  • Conjugate

    GFP

    Excitation source: 488 nm spectral line, argon-ion laser

    Excitation Wavelength: 488 nm

    Emission Wavelength: 530 nm

  • Formulation

    The VLPs are highly immunogenic, so the immunization strategy should be optimized (antigen dose, regimen and adjuvant).

    Supplied as 0.2 μm filtered solution in PBS, Arginine, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 12 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     SSTR2 ELISA

    Immobilized Fluorescent Human SSTR2 Full Length Protein (VLP) (Cat. No. SS2-HF2G3) at 1 μg/mL (100 μL/well) can bind Anti-SSTR2 Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).

    Protocol
  • Identity-DLS

     SSTR2 DLS

    The mean peak Radius of VLP is 55-75 nm with more than 95% intensity as determined by dynamic light scattering (DLS).

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Background

Somatostatin Receptor Type 2, the predominant subtype mediating inhibition of hormone secretion and cell proliferation. It is the primary target for long-acting somatostatin analogs (octreotide, lanreotide) in acromegaly and neuroendocrine tumors. Radiolabeled SSTR2 ligands (PRRT) enable targeted theranostic applications.

Recent Advances

 
Drug Development Progress
  • English Name:

    Somatostatin receptor 2

  • Category:

  • Approved Drugs:

    7 Details

  • Drugs in Clinical Trials:

    29 Details

  • Highest Development Stage:

    Approved

Drug Candidate Licensing
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  • Background