pH Sensitive Anti-Human IgG Labeling Reagent

In in vivo CAR research, the endocytic capacity of tLNP is a key factor for evaluation of the delivery efficiency. Our pH-sensitive Anti-Human IgG Labeling Reagent (Cat. IGG-ZFS307) specifically binds to the Fc region of human IgG antibodies, and the pH-sensitive dye can significantly enhance the fluorescence signal in an acidic environment. This enables FACS analysis to evaluate the endocytic efficiency of IgG-format antibody-conjugated LNPs.

• High signal-to-noise ratio – Strong fluorescence signal with minimal background
• Fc-specific targeting – Preserves antibody–antigen interaction
• Application validated – FACS-ready for tLNP uptake studies

Specifically binds to the Fc region of human IgG without recognizing Fab fragments or mouse IgG isotypes.

Excitation Wavelength: 643 nm
Emission Wavelength: 660 nm

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please protect from light and avoid repeated freeze-thaw cycles.

• -20°C to -70°C for 24 months in lyophilized state;
• -20°C to -70°C for 3 months after reconstitution.