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COADS MSDS

Recombinant Monoclonal Anti-Claudin-18.2 Antibody, Mouse (3B10)

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COADS MSDS
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HCS-S278-20ul
$170.00
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HCS-S278-100ul
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Source

Recombinant Monoclonal Anti-Claudin-18.2 Antibody, Mouse (3B10) is a Claudin-18.2 primary antibody for IHC application.

Antibody Type

Recombinant Monoclonal

Clone

3B10

Isotype

Mouse IgG1, Mouse Kappa

Host Species

Mouse

Reactivity

Human

Specificity

React with Claudin 18.2 protein on the membrane of target cell/tissue; No cross reactivity with Claudin 18.1.

Application
Application
Recommended Use
IHC-P
1: 500 - 1: 2000

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Concentration

0.6~0.9 mg/ml

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS (pH7.4), with Trehalose as protectant.

Please contact us for customized product forms or formulations.

Shipping

Liquid product is shipped at blue ice.

Storage

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • 2°C to 8°C for 14 days;
  • -20°C to -70°C for 12 months.
Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

Background

The Claudin-18.2 (CLDN 18.2) protein, an isoform of Claudin 18, a member of the tight junction protein family, is a highly selective biomarker with limited expression in normal tissues and often abnormal expression during the occurrence and development of various primary malignant tumors, such as gastric cancer/gastroesophageal junction (GC/GEJ) cancer, breast cancer, colon cancer, liver cancer, head and neck cancer, bronchial cancer and non-small-cell lung cancer. Claudin-18.2 participates in the proliferation, differentiation and migration of tumor cells. Recent studies have identified Claudin-18.2 expression as a potential specific marker for the diagnosis and treatment of these tumors.