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B7-H3

B7-H3 Overview

English NameCD276 antigenApproved Drugs0
Drugs in Clinical Trials54Target SynonymB7 homolog 3，PSEC0249，UNQ309/PRO352，B7-H3，CD276 antigen，B7H3，CD276，CD276 Molecule，Costimulatory Molecule，4Ig-B7-H3，B7RP-2
Highest Development StageNDA/BLA
English NameCD276 antigen
Target SynonymB7 homolog 3，PSEC0249，UNQ309/PRO352，B7-H3，CD276 antigen，B7H3，CD276，CD276 Molecule，Costimulatory Molecule，4Ig-B7-H3，B7RP-2
Approved Drugs0
Drugs in Clinical Trials54
Highest Development StageNDA/BLA

B7-H3 Product List

  • Product Category

    Protein (5)Beads (1)Antibody (1)

  • Product Status

    Launched (7)

  • Species

    Human (6)Rabbit (1)

  • Tag

    Fc Tag (1)His Tag (2)His Tag & Avi Tag (1)Fc Tag & Avi Tag (1)- (2)

  • Conjugate

    Unconjugated (3)Biotin-labeled (2)- (1)PE Labeled (1)

Total: 7
  • 1

B7-H3 Background

B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.

B7-H3 Synonyms

B7-H3,CD276,B7 homolog 3
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