Human LILRA1 / CD85i / LIR-6 Protein, His Tag, low endotoxin (MALS verified)

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Cat. No. / Size
Price
Qty
LI1-H52H3-100ug
$410.00
LI1-H52H3-1mg
$2885.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    LILRA1, LIR6, CD85i, LIR-6

  • Source

    Human LILRA1, His Tag (LI1-H52H3) is expressed from human 293 cells (HEK293). It contains AA Pro 17 - Asn 461 (Accession # O75019-1).

    Predicted N-terminus: Pro 17

    Request for sequence
  • Molecular Characterization

    LILRA1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 50.4 kDa. The protein migrates as 65-75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    LILRA1 SDS-PAGE

    Human LILRA1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    LILRA1 SEC-MALS

    The purity of Human LILRA1, His Tag (Cat. No. LI1-H52H3) is more than 95% and the molecular weight of this protein is around 60-75 kDa verified by SEC-MALS.

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Background

Leukocyte immunoglobulin-like receptors (LILRs) are inhibitory, stimulatory or soluble receptors encoded within the leukocyte receptor complex. Some LILRs are extensively polymorphic, and exhibit evidence for balancing selection and association with disease susceptibility. LILRA1 (LIR-6) can recognize MHC (major histocompatibility complex) class I or class I-like molecules, and high levels of sequence similarity among LILRA1, LILRA2 (ILT1), LILRA3 (ILT6) and LILRB1/B2.

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