PE-Labeled Human DLL3 Protein, His Tag (Site-specific conjugation)

Customer Reviews
Cat. No. / Size
Price
Qty
DL3-HP2H7-25tests
$360.00
DL3-HP2H7-200tests
$2245.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    Delta3, delta-like 3 (Drosophila), delta-like protein 3, DLL3, Pudgy, SCDO1, SCDO1delta3

  • Source

    PE-Labeled Human DLL3 Protein, His Tag (DL3-HP2H7) is produced via site-specific conjugation of PE to Human DLL3 Protein, His Tag under optimal conditions with a proprietary technology. Human DLL3 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Leu 492 (Accession # Q9NYJ7-1).

    Predicted N-terminus: Ala 27

    Request for sequence

  • Molecular Characterization

    DLL3 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 52.1 kDa.

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Application

    Please note that this product is NOT compatible to streptavidin detection system.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 0.5% BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Customers Also Viewed

Performance Data

  • Bioactivity-FACS

     DLL3 FACS

    5e5 of anti-DLL3 CAR-293 cells were stained with 100 μL of 1:25 dilution (4 μL stock solution in 100 μL FACS buffer) of PE-Labeled Human DLL3 Protein, His Tag (Cat. No. DL3-HP2H7) and negative control protein respectively. PE signal was used to evaluate the binding activity (QC tested).

    Protocol

Customer Reviews
Writing Reviews

Background

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.

Recent Advances

 
Drug Development Progress
  • English Name:

    Delta-like protein 3

  • Category:

  • Approved Drugs:

    1 Details

  • Drugs in Clinical Trials:

    28 Details

  • Highest Development Stage:

    Approved

Drug Candidate Licensing
More
  • Basic Product Information
  • Product Details
  • Customers Also Viewed
  • Performance Data
  • Customer Reviews
  • Background