IRAK4
IRAK4 Product List
- Product Category
Protein (6)
- Product Status
Launched (6)
- Species
Human (3)Canine (1)Mouse (1)Cynomolgus (1)
- Tag
His Tag (5)GST Tag (1)
- Conjugate
Unconjugated (6)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
 Human | InsectCells | Human IRAK4 Protein, GST Tag (active enzyme, HPLC verified) |  |  |  Add to Cart | ||
| Human | InsectCells | Human IRAK4 Protein, His Tag (active enzyme) |  | | Add to Cart | ||
| Human | InsectCells | Human IRAK4 Protein, His Tag |  | | Add to Cart | ||
 Mouse | InsectCells | Mouse IRAK4 Protein, His Tag (active enzyme) |  | Add to Cart | |||
 Canine | InsectCells | Canine IRAK4 Protein, His Tag (active enzyme) |  | | Add to Cart | ||
 Cynomolgus | InsectCells | Cynomolgus IRAK4 Protein, His Tag (active enzyme) |  | | Add to Cart |
Total: 6
- 1
IRAK4 Background
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Fiztasovimab | NPC-21 | Phase 2 Clinical | Nobelpharma Co Ltd | Cytomegalovirus Infections | Details |
| TRL-345 | CMV-345; TRL-345 | Phase 1 Clinical | Trellis Bioscience LLC | Cytomegalovirus Infections | Details |
- Product List
- Clinical Drug Information