CD6

CD6 Overview

English Name	T-cell differentiation antigen CD6	Approved Drugs	1
Drugs in Clinical Trials	1	Target Synonym	T12，CD6，CD6 Molecule，TP120，T-Cell Differentiation Antigen CD6，CD6 Antigen
Highest Development Stage	Approved

English Name	T-cell differentiation antigen CD6
Target Synonym	T12，CD6，CD6 Molecule，TP120，T-Cell Differentiation Antigen CD6，CD6 Antigen
Approved Drugs	1
Drugs in Clinical Trials	1
Highest Development Stage	Approved

CD6 Product List

Product Category
Protein (6)
Product Status
Launched (6)
Species
Human (3)Cynomolgus (3)
Tag
His Tag (2)His Tag & Avi Tag (2)Fc Tag & Avi Tag (2)
Conjugate
Unconjugated (2)Biotin-labeled (4)

Cat. No.	Species	Host	Product Description	Order Now
HOT CD6-H52H7	Human	HEK293	Human CD6 / TP120 Protein, His Tag	Add to Cart
HOT CD6-H82E3	Human	HEK293	Biotinylated Human CD6 Protein, His,Avitag™ (MALS verified)	Add to Cart
CD6-H82F3	Human	HEK293	Biotinylated Human CD6 / TP120 Protein, Fc,Avitag™ (MALS verified)	Add to Cart
CD6-C52H3	Cynomolgus	HEK293	Cynomolgus CD6 Protein, His Tag (MALS verified)	Add to Cart
CD6-C82E3	Cynomolgus	HEK293	Biotinylated Cynomolgus CD6 Protein, His,Avitag™ (MALS verified)	Add to Cart
CD6-C82F3	Cynomolgus	HEK293	Biotinylated Cynomolgus CD6 / TP120 Protein, Fc,Avitag™ (MALS verified)	Add to Cart

Total: 6

CD6 Background

CD6 (Cluster of Differentiation 6) is a transmembrane protein primarily expressed on T-lymphocytes and certain other immune cells. Structurally, it is characterized by three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule (ALCAM). Functionally, CD6 is critical for the continuation of T cell activation and exhibits scavenger receptor activity. Aberrant CD6 function is associated with diseases such as Multiple Sclerosis. Its paralog is DMBT1.

CD6 Synonyms

CD6,TP120,T12

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells therapy (City of Hope Medical Center)		Phase 1 Clinical	City Of Hope National Medical Center	Diabetes Mellitus, Type 1; Graft vs Host Disease; Hemic and Lymphatic Diseases	Details

Marketed Drug Information

English Name	Research Code	Highest Development Stage	Company	Earliest Brand Name	Earliest Approval Country	Earliest Indication	Earliest Approval Company	Earliest Approval Date	Indication	Clinical Trial
Itolizumab	T-1-hT; EQ-001; T-1-h; h-T1; Bmab-600; Bmab600	Approved	Center Of Molecular Immunology	Alzumab	India	Plaque psoriasis	Biocon Ltd	2013-01-01	Asthma; Coronavirus Disease 2019 (COVID-19); Dermatomyositis; Graft vs Host Disease; Lupus Erythematosus, Cutaneous; Lupus Nephritis; Plaque psoriasis; Psoriasis; Respiratory Distress Syndrome, Adult	Details

Product Reviews

g***t2025-11-28
0People Like
Human CD6 / TP120 Protein, His Tag
We use Human CD16 from AcroBiosystems since many years now for in vitro characterization of antibodies and we are very happy to have well documented certificate to set up our experiments.