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Vitronectin

Vitronectin Overview

English Name	Vitronectin	Approved Drugs	0
Drugs in Clinical Trials	0	Target Synonym	Vitronectin，V75，VN，Serum-spreading factor，Vitronectin (Serum Spreading Factor， Somatomedin B， Complement S-Protein)，Somatomedin B，Epibolin，Serum Spreading Factor，VNT，S-protein，Complement S-Protein，Protein S
Highest Development Stage	Preclinical

English Name	Vitronectin
Target Synonym	Vitronectin，V75，VN，Serum-spreading factor，Vitronectin (Serum Spreading Factor， Somatomedin B， Complement S-Protein)，Somatomedin B，Epibolin，Serum Spreading Factor，VNT，S-protein，Complement S-Protein，Protein S
Approved Drugs	0
Drugs in Clinical Trials	0
Highest Development Stage	Preclinical

Vitronectin Product List

Product Category
Protein (4)Kits (1)
Product Status
Launched (5)
Species
Human (5)
Tag
Tag Free (4)- (1)
Conjugate
Unconjugated (4)- (1)

Cat. No.	Species	Host	Product Description
GMP-VINH19	Human	E. coli	GMP Human Truncated Vitronectin / VTN-N Protein
RES-A103	Human	-	resDetect™ Vitronectin ELISA Kit (Residue Testing)
VIN-H5117	Human	E. coli	Human Truncated Vitronectin / VTN-N Protein, premium grade
VIN-H5118	Human	E. coli	Human Truncated Vitronectin / VTN-N Protein, Research Grade
VIN-H5214	Human	HEK293	Human Vitronectin / VTN Protein, Tag Free, low endotoxin

Total: 5

Vitronectin Background

Vitronectin is also known as S-protein, VN, VTN, V75. Vitronectin, a multifunctional glycoprotein, is involved in coagulation, inhibition of the formation of the membrane attack complex (MAC), cell adhesion and migration, wound healing, and tissue remodeling. The primary cellular source of vitronectin is hepatocytes. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H, respectively. In addition, Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.