Serpin H1 Overview
Molecule Name
Serpin H1
Synonyms
SERPINH1,Serpin H1,HSP47,CBP1,CBP2,SERPINH2,PIG14,AsTP3,Colligin,OI10,PPROM,RA-A47,gp46
Drug Development Progress
Drugs in Clinical Trials2
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
47 kDa heat shock protein，Arsenic-transactivated protein 3，AsTP3，Cell proliferation-inducing gene 14 protein，Rheumatoid arthritis-related antigen RA-A47，HSP47
Background
Serpin H1 is also known as SERPINH1, 47 kDa heat shock protein (HSP47), Collagen-binding protein (Colligin), Arsenic-transactivated protein 3 (AsTP3), which belongs to the serpin family. SERPINH1 binds specifically to collagen. SERPINH1 / HSP47 could be involved as a chaperone in the biosynthetic pathway of collagen.
Serpin H1 Product List
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Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| BMS-986263 | BMS-986263; ND-L02-s0201 | Phase 2 Clinical | Hokkaido University, Nitto Denko, Sapporo Medical University | Fibrosis; Hepatic Insufficiency; Idiopathic Pulmonary Fibrosis; Liver Cirrhosis; Metabolic Dysfunction-Associated Steatotic Liver Disease | Details |
| INV-001 | INV-001 | Phase 2 Clinical | Innovo Therapeutics Inc | Cicatrix | Details |