PAR1 Overview
Molecule Name
Protease-activated receptor-1
Synonyms
F2R,coagulation factor II thrombin receptor,CF2R, HTR, PAR-1, PAR1, TR
Drug Development Progress
Drugs in Clinical Trials3
Approved Drugs0
Highest Development StagePhase 1 Clinical
Target Synonym
Coagulation Factor II (Thrombin) Receptor，Proteinase-Activated Receptor 1，Coagulation Factor II Receptor，Protease-Activated Receptor 1，Protease Activated Receptor 1，Thrombin Receptor，HTR，Receptor， PAR-1，PAR1，F2R，Coagulation Factor II Thrombin Receptor，PAR-1，CF2R，TR
Background
Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants.
PAR1 Product List
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Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Rusalatide | TRAP-508; TP-508 | Phase 1 Clinical | Baylor College Of Medicine, University Of Texas Medical Branch | Radius Fractures; Respiratory Distress Syndrome, Adult | Details |
| Andropaxar-39 | Andropaxar 39; Andropaxar-39 | Phase 1 Clinical | Shandong Qidu Pharmaceutical Co Ltd, Shandong University | Cardiovascular Diseases | Details |
| GP-2102 | GP-2102; GP2102 | Phase 1 Clinical | Nanjing Gritpharma Co Ltd | Dermatitis, Atopic | Details |