Oncostatin M
Oncostatin M Overview
| English Name | Oncostatin M | Approved Drugs | 0 |
| Drugs in Clinical Trials | 0 | Target Synonym | Oncostatin-M，OSM，Oncostatin M，MGC20461 |
| Highest Development Stage | Discontinued | ||
| English Name | Oncostatin M |
| Target Synonym | Oncostatin-M，OSM，Oncostatin M，MGC20461 |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 0 |
| Highest Development Stage | Discontinued |
Oncostatin M Product List
- Product Category
Protein (3)
- Product Status
Launched (3)
- Species
Human (3)
- Tag
Tag Free (2)His Tag & Avi Tag (1)
- Conjugate
Unconjugated (2)Biotin-labeled (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
 Human | HEK293 | Human Oncostatin M (OSM) Protein, premium grade |  |  |  |  Add to Cart | |
| Human | HEK293 | Human Oncostatin M (OSM) (26-221) Protein, premium grade |  | |  | Add to Cart | |
| Human | HEK293 | Biotinylated Human Oncostatin M (OSM) Protein, Avitag™,His Tag |  | | | Add to Cart |
Total: 3
- 1
Oncostatin M Background
Oncostatin M (OSM) serves as a critical maturation factor during the definitive endoderm-to-hepatocyte differentiation of human iPSCs/ESCs. Applied at the hepatoblast-to-hepatocyte transition stage—typically together with HGF and dexamethasone—OSM activates the gp130/LIFRβ receptor complex and downstream JAK/STAT3 and MAPK pathways. This drives robust upregulation of mature hepatic markers including ALB, major CYP enzymes (e.g., CYP3A4, CYP1A2), and bile acid transporters, thereby conferring drug-metabolizing, albumin-secreting, and detoxification capacities essential for functional hepatocyte-like cells and liver organoid models.
Oncostatin M Synonyms
OSM,MGC20461,Oncostatin M
- Overview
- Product List