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Midkine

Midkine Overview

English NameMidkineApproved Drugs0
Drugs in Clinical Trials1Target SynonymMidkine,Midgestation and kidney protein,Neurite outgrowth-promoting factor 2,Neurite outgrowth-promoting protein,Amphiregulin-associated protein,NEGF2,ARAP,FLJ27379,Neurite Growth-Promoting Factor 2,Retinoic Acid Inducible Factor,MK1,MDK,MK
Highest Development StageClinical
English NameMidkine
Target SynonymMidkine,Midgestation and kidney protein,Neurite outgrowth-promoting factor 2,Neurite outgrowth-promoting protein,Amphiregulin-associated protein,NEGF2,ARAP,FLJ27379,Neurite Growth-Promoting Factor 2,Retinoic Acid Inducible Factor,MK1,MDK,MK
Approved Drugs0
Drugs in Clinical Trials1
Highest Development StageClinical

Midkine Product List

  • Product Category

    Protein (1)

  • Product Status

    Launched (1)

  • Species

    Human (1)

  • Tag

    Tag Free (1)

  • Conjugate

    Unconjugated (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeatureOrder Now
MIE-H5117
Human
E. coli
Human Midkine / Mdk Protein, premium grade
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Total: 1
  • 1

Midkine Background

Midkine (MK or MDK), also known as neurite growth-promoting factor 2 (NEGF2), is a protein that in humans is encoded by the MDK gene. Midkine is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin (NEGF1, 46% homologous with MK). It is a nonglycosylated protein, composed of two domains held by disulfide bridges. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair.

Midkine Synonyms

MDK,MEK,Midkine,MK1,MKARAP,NEGF2,Retinoic acid-induced differentiation factor

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
CMK-103CMK-103ClinicalCellmidMyocardial Infarction
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