Ly6E Overview
Molecule Name
Lymphocyte antigen 6E
Synonyms
LY6E,Ly-6E,Ly6E,RIG-E,SCA-2,TSA-1,9804,RIGE,SCA2,TSA1
Drug Development Progress
Drugs in Clinical Trials1
Approved Drugs0
Highest Development StagePhase 1 Clinical
Target Synonym
TSA-1，Retinoic acid-induced gene E protein，SCA-2，TSA1，Ly-6E，RIG-E，RIGE，Stem cell antigen 2，LY6E，Lymphocyte Antigen 6 Family Member E，Retinoic Acid Induced Gene E，Thymic Shared Antigen 1，SCA2，Lymphocyte Antigen 6E，9804，Lymphocyte Antigen 6 Complex， Locus E
Background
This gene belongs to the human Ly6 gene family and encodes a glycosylphosphatidyl-inositol (GPI)-anchored cell surface protein. The protein plays an important role in T cell physiology, oncogenesis and immunological regulation. The protein is also involved in modulation of viral infection by coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2
Ly6E Product List
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Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| M-7437 | M7437; M-7437 | Phase 1 Clinical | Merck Healthcare Kgaa, Darmstadt, Germany, An Affiliate Of Merck Kgaa, Darmstadt, Germany | Solid tumours | Details |