L1R (MPXV)

L1R (MPXV) Product List

Product Category
Protein (2)Antibody (1)
Product Status
Launched (3)
Species
Monkeypox virus (strain Zaire-96-I-16) (1)Mouse (1)Monkeypox virus (Democratic Republic of the Congo) (1)
Tag
His Tag (2)- (1)
Conjugate
Unconjugated (3)

Cat. No.	Species	Host	Product Description	Order Now
L1R-M663	Mouse	HEK293	Monoclonal Anti-Monkeypox-L1R Antibody, Human IgG1 (10D8)	Add to Cart
L1R-M5241	Monkeypox virus (strain Zaire-96-I-16)	HEK293	Monkeypox virus (strain Zaire-96-I-16) L1R Protein, His Tag (HPLC verified)	Add to Cart
L1R-M5243	Monkeypox virus (Democratic Republic of the Congo)	HEK293	Monkeypox virus (Democratic Republic of the Congo) L1R Protein, His Tag (MALS verified)	Add to Cart

Total: 3

L1R (MPXV) Background

Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. L1R is essential for virus assembly and release.

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Sifuvirtide	FS-0101; SFT	Phase 2 Clinical	Tianjin Fusogen Pharmaceuticals Inc	HIV Infections; Acquired Immunodeficiency Syndrome	Details
LP-51	LP-51	Phase 2 Clinical	Institute Of Pathogenic Biology Chinese Academy Of Medical Sciences	HIV Infections; Sjogren's Syndrome	Details
PGT-121	PGT-121	Phase 2 Clinical	International Aids Vaccine Initiative, Theraclone Sciences Inc, The Scripps Research Institute Inc, The Ragon Institute Of Mgh, Mit And Harvard	HIV Infections; Acquired Immunodeficiency Syndrome; Retroviridae Infections; Sexually Transmitted Diseases, Viral; HIV Seropositivity	Details
MPER-656 liposome vaccine	MPER-656	Phase 1 Clinical	National Institute Of Allergy And Infectious Diseases (Niaid)	HIV Infections	Details
Microbicide monoclonal antibody triple combination (Polymun Scientific Immunobiologische Forschung)		Phase 1 Clinical	Polymun Scientific Gmbh	HIV Infections	Details
Elipovimab	GS-9722	Phase 1 Clinical		HIV Infections	Details
CPT-31	CPT-31; CPT31-LA	Phase 1 Clinical	Navigen	Purpura, Thrombocytopenic, Idiopathic; HIV Infections	Details
FB-1002(Frontier Biotechnologies)	FB-1002(前沿生物)	Phase 1 Clinical	Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences	Coronavirus Disease 2019 (COVID-19)	Details

Marketed Drug Information

English Name	Research Code	Highest Development Stage	Company	Earliest Brand Name	Earliest Approval Country	Earliest Indication	Earliest Approval Company	Earliest Approval Date	Indication	Clinical Trial
Albuvirtide	FB-006M	Approved		艾可宁	Mainland China	HIV Infections	Frontier Biotechnologies Inc	2018-05-23	Acquired Immunodeficiency Syndrome; HIV Infections	Details
Enfuvirtide	T-20; R-698; DP-178	Approved	F. Hoffmann-La Roche Ltd	Fuzeon	United States	HIV Infections	F. Hoffmann-La Roche Ltd	2003-03-13	HIV Infections; Acquired Immunodeficiency Syndrome; HIV Seropositivity	Details