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KIR2DL3

KIR2DL3 Overview

English NameKiller cell immunoglobulin-like receptor 2DL3Approved Drugs0
Drugs in Clinical Trials1Target SynonymP58.2 MHC Class-I Specific NK Receptor,MHC Class I NK Cell Receptor,CD158b2 Antigen,KIR-K7b,KIR-K7c,KIR2DS5,CD158b,KIR2DL,NKAT2A,NKAT2B,GL183,NKAT,P58,Receptors, KIR2DL3,Cl-6,Killer Cell Immunoglobulin-Like Receptor Two Domains Long Cytoplasmic Tail 3,Natural Killer Cell Inhibitory Receptor KIR2DL3,Natural Killer Associated Transcript 2,p58.2 MHC class-I-specific NK receptor,Natural killer-associated transcript 2,NKAT-2,NKAT2,p58 natural killer cell receptor clone CL-6,Killer inhibitory receptor cl 2-3,CD158b2,Killer cell immunoglobulin-like receptor 2DL3,KIR2DL3,Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Long Cytoplasmic Tail 3,CD158 Antigen-Like Family Member B2,P58 NK Receptor CL-6,KIR-023GB,KIRCL23,Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 5,Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3
Highest Development StagePhase 2 Clinical
English NameKiller cell immunoglobulin-like receptor 2DL3
Target SynonymP58.2 MHC Class-I Specific NK Receptor,MHC Class I NK Cell Receptor,CD158b2 Antigen,KIR-K7b,KIR-K7c,KIR2DS5,CD158b,KIR2DL,NKAT2A,NKAT2B,GL183,NKAT,P58,Receptors, KIR2DL3,Cl-6,Killer Cell Immunoglobulin-Like Receptor Two Domains Long Cytoplasmic Tail 3,Natural Killer Cell Inhibitory Receptor KIR2DL3,Natural Killer Associated Transcript 2,p58.2 MHC class-I-specific NK receptor,Natural killer-associated transcript 2,NKAT-2,NKAT2,p58 natural killer cell receptor clone CL-6,Killer inhibitory receptor cl 2-3,CD158b2,Killer cell immunoglobulin-like receptor 2DL3,KIR2DL3,Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Long Cytoplasmic Tail 3,CD158 Antigen-Like Family Member B2,P58 NK Receptor CL-6,KIR-023GB,KIRCL23,Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 5,Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3
Approved Drugs0
Drugs in Clinical Trials1
Highest Development StagePhase 2 Clinical

KIR2DL3 Product List

  • Product Category

    Protein (1)

  • Product Status

    Launched (1)

  • Species

    Human (1)

  • Tag

    Fc Tag (1)

  • Conjugate

    Unconjugated (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeatureOrder Now
KI3-H5258
Human
HEK293
Human KIR2DL3 / CD158b2 / NKAT-2 Protein, Fc Tag (MALS verified)
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Total: 1
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KIR2DL3 Background

Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3) is also known as CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, which is a single-pass type I membrane protein and belongs to the immunoglobulin superfamily.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). KIR2DL3 can inhibit the activity of NK cells thus preventing cell lysis.

KIR2DL3 Synonyms

CD158b2

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
LirilumabIPH-21; NN-1975; IPH-2101; IPH-2102; BMS-986015Phase 2 ClinicalNovo Nordisk A/SBone Marrow Neoplasms; Hodgkin Disease; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neoplasms; Smoldering Multiple Myeloma; Squamous Cell Carcinoma of Head and Neck; Urinary Bladder Neoplasms
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  • Clinical Drug Information