HABP1

HABP1 Overview

English Name	HLA-DR antigens-associated invariant chain	Approved Drugs	0
Drugs in Clinical Trials	4	Target Synonym	CLIP，CD74，Ia antigen-associated invariant chain，CD74 Molecule，CD74 Antigen (Invariant Polypeptide Of Major Histocompatibility Complex， Class II Antigen-Associated)，CD74 Molecule， Major Histocompatibility Complex， Class II Invariant Chain，HLA-DR Antigens-Associated Invariant Chain，Ia-Associated Invariant Chain，MHC HLA-DR Gamma Chain，HLA-DR-Gamma，DHLAG，P33，CD74 Antigen，Ia-GAMMA，HLADG，II，Gamma Chain Of Class II Antigens，HLA Class II Histocompatibility Antigen Gamma Chain
Highest Development Stage	Phase 2 Clinical

English Name	HLA-DR antigens-associated invariant chain
Target Synonym	CLIP，CD74，Ia antigen-associated invariant chain，CD74 Molecule，CD74 Antigen (Invariant Polypeptide Of Major Histocompatibility Complex， Class II Antigen-Associated)，CD74 Molecule， Major Histocompatibility Complex， Class II Invariant Chain，HLA-DR Antigens-Associated Invariant Chain，Ia-Associated Invariant Chain，MHC HLA-DR Gamma Chain，HLA-DR-Gamma，DHLAG，P33，CD74 Antigen，Ia-GAMMA，HLADG，II，Gamma Chain Of Class II Antigens，HLA Class II Histocompatibility Antigen Gamma Chain
Approved Drugs	0
Drugs in Clinical Trials	4
Highest Development Stage	Phase 2 Clinical

HABP1 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
His Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature	Order Now
C1P-H5122	Human	E. coli	Human HABP1 / C1QBP Protein, His Tag				Add to Cart

Total: 1

HABP1 Background

Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP), a member of the MAM33 family, is also known as ASF/SF2-associated protein p32, glycoprotein gC1qBP (C1qBP), mitochondrial matrix protein p32 and hyaluronan-binding protein 1, which is a homotrimer that contains three monomers forming a donut-shaped structure with an unusually asymmetric charge distribution on the surface. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. C1QBP has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. Furthermore, C1QBP has been shown to interact with Protein kinase D1, BAT2, PRKCD, PKC alpha and Protein kinase Mζ .

HABP1 Synonyms

C1QBP,GC1QBP,HABP1,SF2P32,p33

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
S-227928	S227928; S-227928	Phase 2 Clinical	Les Laboratoires Servier	Hematologic Neoplasms; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Leukemia, Myeloid, Acute	Details
Influenza A M1 vaccine (Pascal Biosciences)		Phase 1 Clinical	Pascal Biosciences	Influenza A virus infections	Details
adenovector based vaccine (Pascal Biosciences/University of British Columbia)		Phase 1 Clinical		Influenza A virus infections	Details
Bezetabart debotansine	STRO-001; SP7675; SP-7675; BN-301	Phase 1 Clinical	Sutro Biopharma Inc	Lymphoma, B-Cell; Hematologic Neoplasms; Lymphoma, Large B-Cell, Diffuse; Multiple Myeloma; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin	Details