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Menu
Home PageAll MoleculesGITR
GITR
GITR Overview
| English Name | Glucocorticoid-induced tumor necrosis factor receptor-related protein | Approved Drugs | 0 |
| Drugs in Clinical Trials | 4 | Target Synonym | TNFRSF18，TNF Receptor Superfamily Activation-Inducible Protein，ENERGEN，GITR-D，Tumor Necrosis Factor Receptor Superfamily Member 18，CD357 Antigen，Activation-Inducible TNFR Family Receptor，AITR，CD357，GITR，Glucocorticoid-Induced TNFR-Related Protein，Tumor Necrosis Factor Receptor Superfamily， Member 18，TNF Receptor Superfamily Member 18 |
| Highest Development Stage | Phase 2 Clinical | ||
| English Name | Glucocorticoid-induced tumor necrosis factor receptor-related protein |
| Target Synonym | TNFRSF18，TNF Receptor Superfamily Activation-Inducible Protein，ENERGEN，GITR-D，Tumor Necrosis Factor Receptor Superfamily Member 18，CD357 Antigen，Activation-Inducible TNFR Family Receptor，AITR，CD357，GITR，Glucocorticoid-Induced TNFR-Related Protein，Tumor Necrosis Factor Receptor Superfamily， Member 18，TNF Receptor Superfamily Member 18 |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 4 |
| Highest Development Stage | Phase 2 Clinical |
GITR Product List
- Product Category
Protein (7)
- Product Status
Launched (7)
- Species
Human (4)Canine (1)Mouse (2)
- Tag
His Tag (3)Fc Tag (1)Fc Tag & Avi Tag (1)His Tag & Avi Tag (2)
- Conjugate
Unconjugated (4)Biotin-labeled (3)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
HOT GIR-H5228 |  Human | HEK293 | Human GITR / TNFRSF18 Protein, His Tag, low endotoxin (MALS verified) |  |  |  |  Add to Cart |
HOT GIR-H5254 | Human | HEK293 | Human GITR / TNFRSF18 Protein, Fc Tag, low endotoxin |  | | | Add to Cart |
GIR-H82E5 | Human | HEK293 | Biotinylated Human GITR / TNFRSF18 Protein, His,Avitag™ (MALS verified) |  | | | Add to Cart |
GIR-H82F7 | Human | HEK293 | Biotinylated Human GITR / TNFRSF18 Protein, Fc,Avitag™ |  | | | Add to Cart |
GIR-M52H3 |  Mouse | HEK293 | Mouse GITR / TNFRSF18 Protein, His Tag |  | | | Add to Cart |
GIR-M82E3 | Mouse | HEK293 | Biotinylated Mouse GITR / TNFRSF18 Protein, His,Avitag™ (MALS verified) |  | | | Add to Cart |
GIR-C52H6 |  Canine | HEK293 | Canine GITR / TNFRSF18 Protein, His Tag |  | | | Add to Cart |
Total: 7
- 1
GITR Background
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
GITR Synonyms
AITR,GITR,TNFRSF18,CD357
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| BMS-986156 | BMS-986156 | Phase 2 Clinical | Bristol-Myers Squibb Company | Liver Neoplasms; Lung Neoplasms; Neoplasms; Solid tumours; Thoracic Neoplasms | Details |
| Ragifilimab | INCAGN-1876; INCAGN-01876; AGEN-1876; CM-701 | Phase 2 Clinical | Agenus Inc, Ludwig Institute For Cancer Research | Neoplasm Metastasis; Neoplasms | Details |
| Anti-GITR antibody (BMS) | Phase 1 Clinical | Bristol-Myers Squibb Company | Neoplasms | Details | |
| IBI-102 | IBI102; IBI-102 | Phase 1 Clinical | Neoplasms | Details |
Product Reviews
1***32019-09-27
1People LikeI have been using Acro's products for a long time. Whenever there is some concerns on product or technical support is needed, it always gets solved in time. I used the GITR protein for SPR experiments. I have done 6 concentration gradients, and the fitted curve was still very good. The data also met my expectations. I hope we will continue having a good cooperation with ACRO moving forward.
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