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FGL2

FGL2 Product List

Product Category
Protein (2)
Product Status
Launched (2)
Species
Human (2)
Tag
His Tag (2)
Conjugate
Unconjugated (2)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
FG2-H5243	Human	HEK293	Human FGL2 (204-439) Protein, His Tag (MALS verified)
FG2-H5244	Human	HEK293	Human FGL2 Protein, His Tag (HPLC verified)

Total: 2

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FGL2 Background

Fibrinogen-like protein 2, also know as FGL2 is a protein that exhibits pleiotropic effects within the body and is an important immune regulator of both innate and adaptive responses.[7] The protein exists as both a Type II transmembrane protein (with the carboxy terminus on the extracellular side of the plasma membrane) found on the surface of macrophages and endothelial cells and can be constitutively secreted by both CD4+ and CD8+ T cells.

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
XCUR-17	XCUR-17	Phase 1 Clinical	Exicure Inc	Psoriasis	Details

Marketed Drug Information

English Name	Research Code	Highest Development Stage	Company	First Brand Name	First Approved Country	First Indication	First Approved Company	First Approved Date	Indication	Clinical Trial
Brodalumab	IL-17R mAb; MEDI-6365; KHK-4827; AMG-827	Approved	Amgen Inc	Siliq, Lumicef, Kyntheum, 立美芙	Japan	Psoriasis; Arthritis, Psoriatic	Kyowa Kirin Co Ltd	2016-07-04	Non-radiographic axial spondyloarthritis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Scleroderma, Systemic; Psoriasis; Asthma; Arthritis, Psoriatic; Hidradenitis Suppurativa; Crohn Disease; Plaque psoriasis	Details