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DR6

DR6 Overview

English Name	Tumor necrosis factor receptor superfamily member 21	Approved Drugs	0
Drugs in Clinical Trials	0	Target Synonym	CD358，Death receptor 6，Tumor Necrosis Factor Receptor Superfamily， Member 21，TNFR-Related Death Receptor 6，DR6，CD358 Antigen，TNF Receptor Superfamily Member 21，BM-018
Highest Development Stage	Pending

English Name	Tumor necrosis factor receptor superfamily member 21
Target Synonym	CD358，Death receptor 6，Tumor Necrosis Factor Receptor Superfamily， Member 21，TNFR-Related Death Receptor 6，DR6，CD358 Antigen，TNF Receptor Superfamily Member 21，BM-018
Approved Drugs	0
Drugs in Clinical Trials	0
Highest Development Stage	Pending

DR6 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
Fc Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
TN1-H5252	Human	HEK293	Human DR6 / TNFRSF21 Protein, Fc Tag

Total: 1

DR6 Background

Tumor necrosis factor receptor superfamily member 21 (TNFRSF21) is also known as death receptor 6 (DR6), which is a member of the TNF-receptor superfamily. TNFRSF21 contains one death domain and four TNFR-Cys repeats. TNFRSF21 / DR6 has been shown to activate NF-κB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors.