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CEACAM-5

CEACAM-5

CEACAM-5 Overview

Molecule Name
Carcinoembryonic antigen related cell adhesion molecule 5
Synonyms
CEACAM-5,CD66e,CEA,Meconium antigen 100
Drug Development Progress
Drugs in Clinical Trials18
Approved Drugs0
Highest Development StagePhase 3 Clinical
Target Synonym
CEA Cell Adhesion Molecule 5，CEACAM5，Meconium antigen 100，CEA，Carcinoembryonic Antigen Related Cell Adhesion Molecule 5，Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5，Carcinoembryonic Antigen，CD66e Antigen，CD66e
Background
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.

CEACAM-5 Product List

Species
  • Human（12）
  • Cynomolgus（3）
  • Mouse（2）
  • Rhesus macaque（1）
Tag
  • His Tag（8）
  • His Tag & Avi Tag（4）
  • Fc Tag（3）
  • Llama IgG Fc Tag（2）
  • Fc Tag & Avi Tag（1）
Host
  • HEK293（18）
Conjugate
  • Unconjugated（11）
  • Biotin-labeled（5）
  • FITC Labeled（2）
Grade
  • RUO（17）
  • PG (pre-GMP)（1）
Low Endotoxin
  • Yes（4）
  • No（14）
MoleculeCat. No.Product NameSpeciesHostStructurePurityActivitySize&Price
CEACAM-5
HOTAvitagAIDD‑Ready
CE5-H82E0
Biotinylated Human CEACAM-5 / CD66e Protein, His,Avitag™ (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISASPR

$380.00

25ug
CEACAM-5
HOT
CE5-C52H5
Cynomolgus CEACAM-5 / CD66e Protein, His Tag, low endotoxin (MALS verified)
Cynomolgus
HEK293
MALSSDS-PAGE

$405.00

100ug
CEACAM-5
HOTAIDD‑Ready
CE5-H5226
Human CEACAM-5 / CD66e Protein, His Tag (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISASPR

$355.00

100ug
CEACAM-5
CE5-C5257
Cynomolgus CEACAM-5 / CD66e Protein, Llama IgG2b Fc Tag, low endotoxin (MALS verified)
Cynomolgus
HEK293
MALSSDS-PAGE

$360.00

100ug
CEACAM-5
Avitag
CE5-C82E6
Biotinylated Cynomolgus CEACAM-5 / CD66e Protein, His,Avitag™ (MALS verified)
Cynomolgus
HEK293
MALSSDS-PAGE

$360.00

25ug
CEACAM-5
CE5-H5253
Human CEACAM-5 Protein, Fc Tag (HPLC verified)
Human
HEK293
HPLCSDS-PAGE
ELISA

$310.00

100ug
CEACAM-5
CE5-H5259
Human CEACAM-5 Protein, Llama IgG2b Fc Tag, low endotoxin (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISA

$360.00

100ug
CEACAM-5
CE5-H52H3
Human CEACAM-5 / CD66e (145-322) Protein, His Tag (MALS verified)
Human
HEK293
MALSSDS-PAGE

$355.00

100ug
CEACAM-5
CE5-H52H4
Human CEACAM-5 / CD66e (323-500) Protein, His Tag (MALS verified)
Human
HEK293
MALSSDS-PAGE

$355.00

100ug
CEACAM-5
CE5-H52H8
Human CEACAM-5 / CD66e (499-685) Protein, His Tag, low endotoxin (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISA

$390.00

100ug
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Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
Tusamitamab RavtansineSAR-408701; IBI-126Phase 3 ClinicalImmunogen Inc
Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Lung Neoplasms; Metastatic breast cancer; Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms
Details
SGM-101SGM-101Phase 3 ClinicalSurgimab Sas
Brain Diseases; Brain metastases; Brain Neoplasms; Colonic Diseases; Colonic Neoplasms; Colorectal Neoplasms; Gastrointestinal Diseases; Gastrointestinal Neoplasms; Intestinal Diseases; Intestinal Neoplasms; Pancreatic Neoplasms; Rectal Neoplasms
Details
Cancer vaccine (BN ImmunoTherapeutics/National Cancer Institute)CVAC-301; CV-301Phase 2 ClinicalTherion Biologics
Adenocarcinoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Cystadenocarcinoma; Intestinal Neoplasms; Melanoma; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Solid tumours; Urinary Bladder Neoplasms
Details
NEO-201NEO-201Phase 2 ClinicalNational Cancer Institute, Precision Biologics Inc
Carcinoma, Non-Small-Cell Lung; Squamous Cell Carcinoma of Head and Neck; Uterine Cervical Neoplasms; Uterine Neoplasms
Details
Anti-CEA CAR T cell therapy (Shanghai GeneChem)Phase 2 ClinicalShanghai Genechem Co Ltd
Colorectal Neoplasms; Liver Neoplasms
Details
BMS-986490BMS-986490Phase 2 ClinicalBristol-Myers Squibb Company
Solid tumours
Details
LM-24C5LM-24C5Phase 2 ClinicalLaNova Medicines Ltd
Neoplasms; Solid tumours
Details
Precemtabart tocentecanM-9140; M9140Phase 2 ClinicalMerck KGaA, Darmstadt, Germany
Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Pancreatic Neoplasms; Solid tumours; Stomach Neoplasms
Details
MFE-23-CD3z T cell therapy (Cancer Research Technology)Phase 1 ClinicalCancer Research Technology
Neoplasms
Details
anti-CEA CAR T-cell therapy (Shanghai First Song Therapeutics)Phase 1 ClinicalShanghai Simcere Pharmaceutical Co Ltd
Colorectal Neoplasms; Esophageal Neoplasms; Pancreatic Neoplasms; Small Intestine Cancers; Solid tumours; Stomach Neoplasms
Details
125-Iodine-labeled MFE-23Phase 1 ClinicalCancer Research UK
Neoplasms
Details
anti-CEA CAR-T cell therapy (Sorrento/TNK therapeutics/Roger Williams Medical Center)Phase 1 ClinicalBeth Israel Deaconess Medical Center
Adenocarcinoma; Liver Neoplasms; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Solid tumours
Details
CEACAM5-TOPO1 ADC (Bristol-Myers Squibb Company)Phase 1 ClinicalBristol-Myers Squibb Company
Solid tumours
Details
124I-M5APhase 1 ClinicalCity Of Hope National Medical Center, National Cancer Institute
Colorectal Neoplasms
Details
IBI-3020IBI3020; IBI-3020Phase 1 ClinicalXinda Biomedical Technology (Hangzhou) Co Ltd
Neoplasm Metastasis; Solid tumours
Details
SGN-CEACAM5CPF-08046050; SGN-CEACAM5C; SAR445953; SAR-445953Phase 1 ClinicalSanofi, Seagen Inc
Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Gastroesophageal Junction Neoplasms; Small Cell Lung Carcinoma; Solid tumours; Stomach Neoplasms
Details
EBC-129EBC129; EBC-129Phase 1 ClinicalExperimental Drug Development Centre
Solid tumours
Details
GB-5012GB-5012ClinicalShanghai Genbase Biotechnology Co Ltd
Colonic Neoplasms
Details
Customer Reviews
  • n***l2026-08-21
    Human CEACAM-5 / CD66e Protein, His Tag (MALS verified)
    This protein was purchased for target testing. The product was very easy to reconstitute and produced accurate results. The shipping speed of the product was more efficient than estimated which was greatly appreciated. We enjoy ordering high quality products from Acro.