CD52

CD52 Overview

English Name	CAMPATH-1 antigen	Approved Drugs	1
Drugs in Clinical Trials	5	Target Synonym	Epididymis Secretory Sperm Binding Protein Li 171mP，CD52 Antigen (CAMPATH-1 Antigen)，Epididymal Secretory Protein E5，He5，CDW52 Antigen (CAMPATH-1 Antigen)，CD52 Antigen，HEL-S-171mP，EDDM5，CD52，CDw52，Cambridge pathology 1 antigen，Human epididymis-specific protein 5，CAMPATH-1 antigen，CD52 Molecule
Highest Development Stage	Approved

English Name	CAMPATH-1 antigen
Target Synonym	Epididymis Secretory Sperm Binding Protein Li 171mP，CD52 Antigen (CAMPATH-1 Antigen)，Epididymal Secretory Protein E5，He5，CDW52 Antigen (CAMPATH-1 Antigen)，CD52 Antigen，HEL-S-171mP，EDDM5，CD52，CDw52，Cambridge pathology 1 antigen，Human epididymis-specific protein 5，CAMPATH-1 antigen，CD52 Molecule
Approved Drugs	1
Drugs in Clinical Trials	5
Highest Development Stage	Approved

CD52 Product List

Product Category
Protein (3)Antibody (2)
Product Status
Launched (5)
Species
Human (5)
Tag
Fc Tag & Avi Tag (1)Fc Tag (1)His Tag & Avi Tag (1)- (2)
Conjugate
Biotin-labeled (2)Unconjugated (3)

Cat. No.	Species	Host	Product Description	Order Now
HOT CD2-H82E8	Human	HEK293	Biotinylated Human CD52 Protein, His,Avitag™	Add to Cart
CD2-C263G1	Human	HEK293	Monoclonal Anti-CD52 Antibody, Human IgG1, premium grade	Add to Cart
CD2-C263GN	Human	HEK293	Monoclonal Anti-CD52 Antibody, Human IgG1, Research Grade	Add to Cart
CD2-H525a	Human	HEK293	Human CD52 Protein, Fc Tag	Add to Cart
CD2-H82F3	Human	HEK293	Biotinylated Human CD52 Protein, Fc,Avitag™	Add to Cart

Total: 5

CD52 Background

CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.It is widely expressed on the cell surface of immune cells, such as mature lymphocytes, natural killer cells (NK), eosinophils, neutrophils, monocytes/macrophages, and dendritic cells (DCs).ligation of cell surface CD52 molecules may offer costimulatory signals for T-cell activation and proliferation.

CD52 Synonyms

CDW52,HE5,CD52,CAMPATH-1 antigen

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Alemtuzumab biosimilar (Zhangjiang Biotechnology)		Phase 2 Clinical	Shanghai Zhangjiang Biotechnology Co Ltd	Leukemia, Lymphocytic, Chronic, B-Cell	Details
ALLO-647	ALLO-647	Phase 2 Clinical	Allogene Therapeutics Inc	Carcinoma, Renal Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Multiple Myeloma	Details
Alemtuzumab Biosimilars(Cellectis)	CLLS-52; CLLS52	Phase 2 Clinical	Cellectis Sa	Leukemia, Myeloid, Acute; Lymphoma, B-Cell; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	Details
Recombinant anti-CD52 humanized monoclonal antibody (Lanzhou Institute Of Biological Products/Shanghai Taiyin Biotechnology)		Phase 1 Clinical	Lanzhou Institute Of Biological Products Co Ltd, Shanghai Taiyin Biotechnology Co Ltd	Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic; Leukemia, Prolymphocytic, T-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell	Details
Alemtuzumab biosimilar(BioXpress)	BX-1523; BXT-1523	Clinical	Bioxpress Therapeutics Sa	Leukemia, B-Cell; Multiple Sclerosis	Details

Marketed Drug Information

English Name	Research Code	Highest Development Stage	Company	Earliest Brand Name	Earliest Approval Country	Earliest Indication	Earliest Approval Company	Earliest Approval Date	Indication	Clinical Trial
Alemtuzumab	LDP-03; GZ-402673	Approved	Bayer AG, Genzyme Corp	Campath, Lemtrada, MabCampath	United States	Multiple Sclerosis	Genzyme Corp	2001-05-07	Anemia, Aplastic; Anemia, Sickle Cell; Bone marrow transplant rejection; Diabetes Mellitus, Type 1; Fallopian Tube Neoplasms; Graft Rejection; Graft vs Host Disease; Hematologic Neoplasms; Hodgkin Disease; Kidney Diseases; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukemia, Prolymphocytic, T-Cell; Leukemia, T-Cell; Leukemia-Lymphoma, Adult T-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Lymphoproliferative Disorders; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Mycosis Fungoides; Myelodysplastic Syndromes; Myositis, Inclusion Body; Ovarian Neoplasms; Pancytopenia; Peritoneal Neoplasms; Rejection of renal transplantation; Sezary Syndrome; Waldenstrom Macroglobulinemia	Details