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CD5
CD5 Overview
| English Name | T-cell surface glycoprotein CD5 | Approved Drugs | 0 |
| Drugs in Clinical Trials | 13 | Target Synonym | Epididymis Secretory Sperm Binding Protein，CD5，Lymphocyte antigen T1/Leu-1，T-cell surface glycoprotein CD5，CD5 Molecule，CD5 Antigen (P56-62)，LEU1，CD5 Antigen，T1，CD5 Antigens |
| Highest Development Stage | Phase 2 Clinical | ||
| English Name | T-cell surface glycoprotein CD5 |
| Target Synonym | Epididymis Secretory Sperm Binding Protein，CD5，Lymphocyte antigen T1/Leu-1，T-cell surface glycoprotein CD5，CD5 Molecule，CD5 Antigen (P56-62)，LEU1，CD5 Antigen，T1，CD5 Antigens |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 13 |
| Highest Development Stage | Phase 2 Clinical |
CD5 Product List
- Product Category
Protein (17)Antibody (2)Kits (1)Cell (1)
- Product Status
Launched (21)
- Species
Human (14)Mouse (3)Rhesus macaque (3)Rabbit (1)
- Tag
His Tag (7)His Tag & Avi Tag (4)Fc Tag & Avi Tag (2)Fc Tag (4)- (4)
- Conjugate
Unconjugated (6)FITC Labeled (2)Biotin-labeled (6)PE Labeled (2)AF647 Labeled (1)AF488 Labeled (2)- (2)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
HOT CD5-H52H5 |  Human | HEK293 | Human CD5 Protein, His Tag, low endotoxin |  |  |  |  Add to Cart |
HOT CD5-H82E5 | Human | HEK293 | Biotinylated Human CD5 Protein, His,Avitag™, premium grade |  | | | Add to Cart |
HOT CD5-HP2H6 | Human | HEK293 | PE-Labeled Human CD5 Protein, His Tag (Site-specific conjugation) |  |  | Add to Cart | |
HOT GMP-CD5H24 | Human | HEK293 | GMP Biotinylated Human CD5 Protein, His,Avitag™ |  | | Add to Cart | |
HOT CD5-M82E3 |  Mouse | HEK293 | Biotinylated Mouse CD5 Protein, His,Avitag™ (MALS verified) |  | | Add to Cart | |
HOT CD5-R52H3 |  Rhesus macaque | HEK293 | Rhesus macaque CD5 Protein, His Tag (MALS verified) |  | | | Add to Cart |
CD5-H5253 | Human | HEK293 | Human CD5 Protein, Fc Tag, low endotoxin (MALS verified) |  | | | Add to Cart |
CD5-H5255 | Human | HEK293 | Human CD5 Protein, Fc Tag (MALS verified) |  | | | Add to Cart |
CD5-H52H2 | Human | HEK293 | FITC-Labeled Human CD5 Protein, His Tag |  | | Add to Cart | |
CD5-H82F3 | Human | HEK293 | Biotinylated Human CD5 Protein, Fc,Avitag™ (MALS verified) |  | | | Add to Cart |
Total: 21
- 1
- 2
- 3
CD5 Background
T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.
CD5 Synonyms
CD5,LEU1
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| CD5-targeted CAR-T cells therapy(Senlang Biotechnology) | Phase 2 Clinical | Hebei Senlang Biological Technology Co Ltd | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details | |
| CD5/CD7-Specific CAR-T Cells therapy(Essen Biotech) | BAH246; BAH-246; EB-BH2026 | Phase 2 Clinical | Essen Biotech | Central Nervous System Diseases; Leukemia, Prolymphocytic, T-Cell; Leukemia, T-Cell; Lymphoma, T-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details |
| CD5 CAR T Cells therapy(Beijing GoBroad Hospital) | Phase 2 Clinical | Beijing GoBroad Hospital | Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details | |
| MB-105(March Biosciences) | MB-105(March Biosciences) | Phase 2 Clinical | March Biosciences Inc | Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details |
| anti-CD5 CAR T-cell therapy (Beijing Boren Hospital) | Phase 1 Clinical | Beijing Gao Boren Hospital Co Ltd | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details | |
| CD5CAR | CD5CAR | Phase 1 Clinical | iCell Gene Therapeutics LLC | Lymphoma, Non-Hodgkin; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details |
| CT-125A | CT-125A; RD-125 | Phase 1 Clinical | Nanjing Iaso Biotherapeutics Co Ltd | Hematologic Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Plasmablastic Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details |
| CD5 Targeting Chimeric Antigen Receptor NK Cells (CAR-NK) thrapy(Precision Biotechnology) | Phase 1 Clinical | Chongqing Precision Biotechnology Co Ltd | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details | |
| CD5 CAR T-cells therapy(Yake Biotechnology) | Phase 1 Clinical | Shanghai YaKe Biotechnology Co Ltd | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details | |
| AB-205 (Artiva Biotherapeutics/GC Cell) | CD5 CAR-NK; GCC-2005; GL-205; GCC2005 | Phase 1 Clinical | GC Cell Corp | Lymphoma, T-Cell | Details |
| Autologous CAR-T cell therapy(Vittoria Biotherapeutics) | VIPER-101; Senza5 CART5; VIPER101 | Phase 1 Clinical | Vittoria Biotherapeutics Inc | Lymphoma, T-Cell | Details |
| CD5 CAR T-Cells (Baylor College of Medicine) | Phase 1 Clinical | Baylor College Of Medicine | Lymphoma, Non-Hodgkin; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details | |
| CD5 CAR-T Therapy(Xuanwu Hospital) | Phase 1 Clinical | Xuanwu Hospital Of Capital Medical University | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Details |
- Overview
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- Clinical Drug Information
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