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Home PageAll MoleculesCD45RA
CD45RA
CD45RA Overview
| English Name | Leukocyte common antigen | Approved Drugs | 0 |
| Drugs in Clinical Trials | 7 | Target Synonym | PTPRC，T200，CD45，Protein Tyrosine Phosphatase， Receptor Type C，CD45 Antigen，L-CA，Protein Tyrosine Phosphatase， Receptor Type， C Polypeptide，Receptor-Type Tyrosine-Protein Phosphatase C，T200 Leukocyte Common Antigen，Leukocyte Common Antigen，T200 Glycoprotein，EC 3.1.3.48，CD45R，GP180，B220，LCA，LY5，Leukocyte Common Antigens，Protein Tyrosine Phosphatase Receptor Type C，EC:3.1.3.48 |
| Highest Development Stage | Phase 3 Clinical | ||
| English Name | Leukocyte common antigen |
| Target Synonym | PTPRC，T200，CD45，Protein Tyrosine Phosphatase， Receptor Type C，CD45 Antigen，L-CA，Protein Tyrosine Phosphatase， Receptor Type， C Polypeptide，Receptor-Type Tyrosine-Protein Phosphatase C，T200 Leukocyte Common Antigen，Leukocyte Common Antigen，T200 Glycoprotein，EC 3.1.3.48，CD45R，GP180，B220，LCA，LY5，Leukocyte Common Antigens，Protein Tyrosine Phosphatase Receptor Type C，EC:3.1.3.48 |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 7 |
| Highest Development Stage | Phase 3 Clinical |
CD45RA Product List
- Product Category
Protein (1)Antibody (1)
- Product Status
Launched (2)
- Species
Human (1)Mouse (1)
- Tag
His Tag (1)- (1)
- Conjugate
Unconjugated (1)PE Labeled (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
CD5-H52H9 |  Human | HEK293 | Human CD45RA / PTPRC protein, His Tag |  |  |  Add to Cart | |
FABm040-01 |  Mouse | - | PE-Labeled Monoclonal Anti-Human CD45RA Antibody, Mouse IgG2b (AS624) (0.03% Proclin) |  | Add to Cart |
Total: 2
- 1
CD45RA Background
CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.
CD45RA Synonyms
B220, CD45, CD45R, GP180, IMD105, L-CA, LCA, LY5, T200
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Immunomodulatory progenitor cell therapy (Celixir) | Phase 3 Clinical | Celixir | Cardiomyopathies; Endomyocardial Fibrosis | Details | |
| I-131-Apamistamab | BC8-I-131; BC-8; 131IBC8; I-131 BC-8 | Phase 3 Clinical | Fred Hutchinson Cancer Research Center | Anemia, Refractory, with Excess of Blasts; Anemia, Sickle Cell; Anemia, Sideroblastic; Angioimmunoblastic T-cell Lymphoma; Burkitt Lymphoma; Graft vs Host Disease; Hematopoietic stem cell transplantation (HSCT); Hodgkin Disease; Intraocular Lymphoma; Leukemia; Leukemia, Hairy Cell; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia-Lymphoma, Adult T-Cell; Lymphoma; Lymphoma, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Extranodal NK-T-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Large-Cell, Immunoblastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Lymphomatoid Granulomatosis; Mycosis Fungoides; Myelodysplastic Syndromes; Neoplasms, Gonadal Tissue; Neoplastic Cells, Circulating; Pancytopenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sezary Syndro | Details |
| At 211 MAb BC8-B10 | Phase 2 Clinical | Fred Hutchinson Cancer Research Center | Neoplasms | Details | |
| 211At-BC8-B10 | 211At-BC8-B10 | Phase 2 Clinical | Fred Hutchinson Cancer Research Center, National Cancer Institute | Hematologic Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma | Details |
| CD45BE-HSPC cells therapy (Kite Pharma) | Phase 1 Clinical | Kite Pharma | Hodgkin Disease; Lymphoma, B-Cell; Lymphoma, T-Cell; Richter's Syndrome | Details | |
| CART-45 cells therapy (Kite Pharma) | Phase 1 Clinical | Kite Pharma | Hodgkin Disease; Lymphoma, B-Cell; Lymphoma, T-Cell; Richter's Syndrome | Details | |
| TSC-102 | TSC-102-A03; TSC-102-A0301; TSC-102; TSC-102-A01 | Phase 1 Clinical | TScan Therapeutics Inc | Hematologic Neoplasms; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma | Details |
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