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Home PageAll MoleculesCD44
CD44
CD44 Overview
| English Name | CD44 antigen | Approved Drugs | 0 |
| Drugs in Clinical Trials | 10 | Target Synonym | Hermes Antigen，Hyaluronate Receptor，Cell Surface Glycoprotein CD44，MC56，PGP-1，CD44，CDW44，GP90 Lymphocyte Homing/Adhesion Receptor，MIC4，LHR，Hematopoietic Cell E- And L-Selectin Ligand，CD44 Antigen (Homing Function And Indian Blood Group System)，MDU3，Extracellular Matrix Receptor III，Heparan Sulfate Proteoglycan，HUTCH-I，ECMR-III，Epican，Chondroitin Sulfate Proteoglycan 8，Soluble CD44，MDU2，Pgp1，CSPG8，HCELL，Phagocytic Glycoprotein 1，Indian Blood Group Antigen，IN，Phagocytic Glycoprotein I，CD44 Molecule (Indian Blood Group)，CD44 Antigen，PGP-I，Homing Function And Indian Blood Group System，Hyaluronan Receptors，CD44R |
| Highest Development Stage | Phase 3 Clinical | ||
| English Name | CD44 antigen |
| Target Synonym | Hermes Antigen，Hyaluronate Receptor，Cell Surface Glycoprotein CD44，MC56，PGP-1，CD44，CDW44，GP90 Lymphocyte Homing/Adhesion Receptor，MIC4，LHR，Hematopoietic Cell E- And L-Selectin Ligand，CD44 Antigen (Homing Function And Indian Blood Group System)，MDU3，Extracellular Matrix Receptor III，Heparan Sulfate Proteoglycan，HUTCH-I，ECMR-III，Epican，Chondroitin Sulfate Proteoglycan 8，Soluble CD44，MDU2，Pgp1，CSPG8，HCELL，Phagocytic Glycoprotein 1，Indian Blood Group Antigen，IN，Phagocytic Glycoprotein I，CD44 Molecule (Indian Blood Group)，CD44 Antigen，PGP-I，Homing Function And Indian Blood Group System，Hyaluronan Receptors，CD44R |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 10 |
| Highest Development Stage | Phase 3 Clinical |
CD44 Product List
- Product Category
Protein (2)Antibody (2)
- Product Status
Launched (4)
- Species
Human (2)Rabbit (1)Mouse (1)
- Tag
His Tag (1)Fc Tag (1)- (2)
- Conjugate
Unconjugated (3)PE Labeled (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
CD4-H5226 |  Human | HEK293 | Human CD44 Protein, His Tag |  |  |  |  Add to Cart |
PG1-H5255 | Human | HEK293 | Human CD44 Protein, Fc Tag (HPLC-verified) |  | | | Add to Cart |
FABm039-01 |  Mouse | - | PE-Labeled Monoclonal Anti-Human CD44 Antibody, Mouse IgG1 (AS625) (0.03% Proclin) |  | Add to Cart | ||
HGS-S246 |  Rabbit | - | Recombinant Monoclonal Anti-CD44 Antibody, Rabbit (5G3) | Add to Cart |
Total: 4
- 1
CD44 Background
CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types. CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 function is controlled by its posttranslational modifications. One critical modification involves discrete sialofucosylations rendering the selectin-binding glycoform of CD44 called HCELL (for Hematopoietic Cell E-selectin/L-selectin Ligand). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms.
CD44 Synonyms
CD44,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1,Epican
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Paclitaxel/Hyaluronic acid | Phase 3 Clinical | Fidia Pharma | Carcinoma, Papillary; Urinary Bladder Neoplasms | Details | |
| CA-102N | CA-102N | Phase 2 Clinical | Holy Stone Healthcare Co Ltd | Colorectal Neoplasms; Solid tumours | Details |
| P-134 | P-134; P134 | Phase 2 Clinical | Tianjin Tasly Pharmaceutical Co Ltd | Glioblastoma | Details |
| Rosuvastatin liposome encapsulated therapy (Beijing Inno Medicine) | YN001; YN-001 | Phase 2 Clinical | Beijing Inno Medicine Co Ltd | Atherosclerosis; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Artery Disease; Erectile Dysfunction | Details |
| AMT-116(Multitude Therapeutics) | AMT-116; AMT-116-ADC | Phase 2 Clinical | Multitude Therapeutics Inc | Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Head and Neck Neoplasms; Solid tumours | Details |
| Hyaluronic acid/Fluorouracil | HA-5FU; HA-5-fluorouracil; Hyaluronic acid-5-fluorouracil complex; Hyaluronan acid-5-fluorouracil complex | Phase 2 Clinical | Alchemia Ltd, Monash University | Colorectal Neoplasms | Details |
| AMC-303 | AMC-303; HP-558 | Phase 1 Clinical | Amcure Gmbh | Esophageal Squamous Cell Carcinoma; Solid tumours | Details |
| Clodronic acid/Hyaluronic acid | Phase 1 Clinical | Abiogen Pharma Spa | Osteoarthritis | Details | |
| 177Lu-AKIR001 | 177Lu-AKIR001 | Phase 1 Clinical | Akiram Therapeutics AB | Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Neoplasms; Thyroid Carcinoma, Anaplastic; Uterine Cervical Neoplasms; Vulvar Neoplasms | Details |
| BGC-0228 | BGC-0228 | Phase 1 Clinical | Brightgene Bio-Medical Technology Co Ltd | Solid tumours | Details |
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