CD200

CD200 Overview

English NameOX-2 membrane glycoproteinApproved Drugs0
Drugs in Clinical Trials1Target SynonymMy033,CD200,CD200 Antigen,Antigen Identified By Monoclonal Antibody MRC OX-2,MOX1,OX-2 Membrane Glycoprotein,OX-2,MRC,CD200 Molecule,MOX2
Highest Development StagePhase 2 Clinical
English NameOX-2 membrane glycoprotein
Target SynonymMy033,CD200,CD200 Antigen,Antigen Identified By Monoclonal Antibody MRC OX-2,MOX1,OX-2 Membrane Glycoprotein,OX-2,MRC,CD200 Molecule,MOX2
Approved Drugs0
Drugs in Clinical Trials1
Highest Development StagePhase 2 Clinical

CD200 Product List

  • Product Category

    Protein (4)

  • Product Status

    Launched (4)

  • Species

    Human (3)Mouse (1)

  • Tag

    Fc Tag (1)His Tag (1)Fc Tag & Avi Tag (2)

  • Conjugate

    Unconjugated (2)Biotin-labeled (2)

CD200 Background

CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.

CD200 Synonyms

CD200,MOX1,MOX2,MRC,OX-2,My033

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
P-00623ME-00610; P-006; 23ME’610Phase 2 Clinical23andme IncCarcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Fallopian Tube Neoplasms; Microsatellite instability-high cancer; Neuroendocrine Tumors; Peritoneal Neoplasms; Small Cell Lung Carcinoma; Solid tumours
Details
  • Overview
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  • Clinical Drug Information