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CCL19

CCL19 Overview

English Name	C-C motif chemokine 19	Approved Drugs	0
Drugs in Clinical Trials	1	Target Synonym	Beta-chemokine exodus-3，CK beta-11，Epstein-Barr virus-induced molecule 1 ligand chemokine，EBI1 ligand chemokine，ELC，Macrophage inflammatory protein 3 beta，MIP-3-beta，Small-inducible cytokine A19，MIP3B，SCYA19
Highest Development Stage	Phase 1 Clinical

English Name	C-C motif chemokine 19
Target Synonym	Beta-chemokine exodus-3，CK beta-11，Epstein-Barr virus-induced molecule 1 ligand chemokine，EBI1 ligand chemokine，ELC，Macrophage inflammatory protein 3 beta，MIP-3-beta，Small-inducible cytokine A19，MIP3B，SCYA19
Approved Drugs	0
Drugs in Clinical Trials	1
Highest Development Stage	Phase 1 Clinical

CCL19 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
Tag Free (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
CC9-H5215	Human	HEK293	Human CCL19 / MIP-3 beta Protein, Tag Free (HPLC verified)

Total: 1

CCL19 Background

C-C motif chemokine 19(CCL19) is as known as CK beta-11, ELC, MIP3B and SCYA19. May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

CCL19 Synonyms

CCL19,MIP-3 beta,MIP-3-beta,ELC,MIP3B,SCYA19,EBI1 ligand chemokine

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Anti-GPC3 chimeric antigen receptor T cell therapy (Hunan Zhaotai Yongren Biotech/Guangdong Zhaotai Invivo Biomedicine)		Phase 1 Clinical	Guangdong Zhaotai Invivo Biomedicine Co Ltd, Hunan Zhaotai Yongren Biotech Co Ltd	Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung	Details