Cadherin-6

Cadherin-6 Overview

English Name	Cadherin-6	Approved Drugs	0
Drugs in Clinical Trials	5	Target Synonym	Kidney cadherin，K-cadherin，Cadherin 6， Type 2， K-Cadherin (Fetal Kidney)，K-Cadherin，Cadherin-6，Kidney Cadherin，CAD6，KCAD
Highest Development Stage	Phase 3 Clinical

English Name	Cadherin-6
Target Synonym	Kidney cadherin，K-cadherin，Cadherin 6， Type 2， K-Cadherin (Fetal Kidney)，K-Cadherin，Cadherin-6，Kidney Cadherin，CAD6，KCAD
Approved Drugs	0
Drugs in Clinical Trials	5
Highest Development Stage	Phase 3 Clinical

Cadherin-6 Product List

Product Category
Protein (9)Cell (1)Beads (1)
Product Status
Launched (11)
Species
Human (7)Cynomolgus / Rhesus macaque (2)Mouse (1)Rat (1)
Tag
His Tag (4)Fc Tag (4)His Tag & Avi Tag (1)- (2)
Conjugate
Unconjugated (8)Biotin-labeled (1)- (2)

Cat. No.	Species	Host	Product Description	Order Now
HOT CA6-H5229	Human	HEK293	Human Cadherin-6 / KCAD / CDH6 Protein, His Tag, low endotoxin (HPLC verified)	Add to Cart
HOT CA6-H5258	Human	HEK293	Human Cadherin-6 / KCAD / CDH6 Protein, Fc Tag (MALS verified)	Add to Cart
HOT CA6-H82E3	Human	HEK293	Biotinylated Human Cadherin-6 / KCAD / CDH6 Protein, His,Avitag™ (MALS verified)	Add to Cart
HOT CA6-C52H3	Cynomolgus / Rhesus macaque	HEK293	Cynomolgus / Rhesus macaque Cadherin-6 / KCAD / CDH6 Protein, His Tag, low endotoxin	Add to Cart
CA6-H5253	Human	HEK293	Human Cadherin-6 / KCAD / CDH6 (19-486) Protein, Fc Tag (MALS verified)	Add to Cart
CA6-H5254	Human	HEK293	Human Cadherin-6 / KCAD / CDH6 (269-383) Protein, Fc Tag	Add to Cart
CHEK-ATP127	Human	HEK293	HEK293/Human Cadherin-6 Stable Cell Line	Add to Cart
MBC-K196	Human	-	Human Cadherin-6 coupled magnetic beads (2 µm)	Add to Cart
CA6-M52H8	Mouse	HEK293	Mouse Cadherin-6 / KCAD / CDH6 Protein, His Tag	Add to Cart
CA6-C5253	Cynomolgus / Rhesus macaque	HEK293	Cynomolgus / Rhesus macaque Cadherin-6 / KCAD / CDH6 Protein, Fc Tag (MALS verified)	Add to Cart

Total: 11

Cadherin-6 Background

Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.

Cadherin-6 Synonyms

CDH6,CAD6,KCAD,K-cadherin,Cadherin-6

Antibody Project Trading Platform

Project Name	Project Stage	Molecule Type	Molecule Source	Disease Area	Indication
CDH6 mAb - 01	PCC	Monoclonal	Humanized Mouse	Solid Tumor	Ovarian cancer,Renal cell carcinoma

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Raludotatug deruxtecan	DS-6000a; DS6000a; DS-6000; R-DXd; MK-5909	Phase 3 Clinical	Daiichi Sankyo Co Ltd	Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Fallopian Tube Neoplasms; Gastrointestinal Neoplasms; Lung Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Solid tumours	Details
QLS-5133	QLS-5133; QLS5133	Phase 2 Clinical	Qilu Pharmaceutical Co Ltd	Solid tumours	Details
HS-20124	HS-20124; HS20124	Phase 1 Clinical	Hansoh BioMedical R&D Company	Solid tumours	Details
SIM-0505	SIM-0505	Phase 1 Clinical	Hainan Xiansheng Re Ming Pharmaceutical Co Ltd	Solid tumours	Details
AMT-707	AMT-707; CUSP-06	Phase 1 Clinical	Multitude Therapeutics Inc	Carcinoma, Renal Cell; Cholangiocarcinoma; Ovarian Neoplasms; Solid tumours	Details

Product Reviews

1***62022-08-09
1People Like
Human Cadherin-6 / KCAD / CDH6 Protein, His Tag, low endotoxin (HPLC verified)
Validated by SPR, measured monovalent affinity, anti-human FC chip, load diluted antibody, added diluted CDH6, His tag, with the affinity constant of 4.72 nM.