ALPP

ALPP Overview

English Name	Alkaline phosphatase, placental type	Approved Drugs	0
Drugs in Clinical Trials	2	Target Synonym	Alkaline phosphatase Regan isozyme，Placental alkaline phosphatase 1，PLAP-1
Highest Development Stage	Phase 2 Clinical

English Name	Alkaline phosphatase, placental type
Target Synonym	Alkaline phosphatase Regan isozyme，Placental alkaline phosphatase 1，PLAP-1
Approved Drugs	0
Drugs in Clinical Trials	2
Highest Development Stage	Phase 2 Clinical

ALPP Product List

Product Category
Protein (4)Antibody (1)
Product Status
Launched (5)
Species
Cynomolgus (1)Human (2)Mouse (1)Rat (1)
Tag
His Tag (3)- (1)His Tag & Avi Tag (1)
Conjugate
Unconjugated (4)Biotin-labeled (1)

Cat. No.	Species	Host	Product Description	Order Now
HOT ALP-H52H3	Human	HEK293	Human ALPP Protein, His Tag (active enzyme, MALS verified)	Add to Cart
HOT ALP-H82E3	Human	HEK293	Biotinylated Human ALPP Protein, His,Avitag™ (active enzyme, MALS verified)	Add to Cart
HOT ALP-R52H4	Rat	HEK293	Rat ALPP Protein, His Tag (active enzyme)	Add to Cart
HCS-S312	Mouse	-	Recombinant Monoclonal Anti-ALPP Antibody, Mouse (1B10)	Add to Cart
ALP-C52H3	Cynomolgus	HEK293	Cynomolgus ALPP Protein, His Tag (active enzyme)	Add to Cart

Total: 5

ALPP Background

ALPP is highly expressed in a variety of solid tumors, including ovarian, endometrial, germ cell, non-small cell lung, bladder and gastric cancers.In normal tissues, it is expressed in the placenta and low in lung and reproductive tissues.ALPP is a membrane protein and exits as a homodimer.

ALPP Synonyms

PLAP

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Retroviral vector-transduced autologous T cells to express anti-ALPP CARs (TCRCure Biopharma Corporation)		Phase 2 Clinical	Xinqiao Hospital, Army Medical University	Endometrial Neoplasms; Ovarian Neoplasms; Solid tumours	Details
anti-ALPP CAR T-cell therapy (TCRCure Biopharma)	TC-A101	Phase 1 Clinical	Tcrcure Biopharma Ltd	Solid tumours	Details