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A29L (MPXV)

A29L (MPXV) Product List

Product Category
Protein (2)Antibody (1)
Product Status
Launched (3)
Species
Monkeypox virus (strain Zaire-96-I-16) (1)Mouse (1)Monkeypox virus (Democratic Republic of the Congo) (1)
Tag
His Tag (2)- (1)
Conjugate
Unconjugated (3)

Cat. No.	Species	Host	Product Description
A2L-M577	Mouse	HEK293	Monoclonal Anti-Monkeypox-A29L Antibody, Human IgG1 (3H9) (MALS verified)
A2L-M52H3	Monkeypox virus (strain Zaire-96-I-16)	HEK293	Monkeypox virus (strain Zaire-96-I-16) A29L Protein, His Tag
A2L-M52H4	Monkeypox virus (Democratic Republic of the Congo)	HEK293	Monkeypox virus (Democratic Republic of the Congo) A29L Protein, His Tag

Total: 3

A29L (MPXV) Background

Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. A29L binds to cell surface heparin to promote fusion of viral membrane with host plasma membrane.

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Fepixnebart	LY-3016859	Phase 2 Clinical	Eli Lilly And Company	Diabetic Neuropathies; Osteoarthritis, Knee; Diabetic Nephropathies; Osteoarthritis; Low Back Pain	Details