user
menu
letter
Sign InRegister
langEnglisharrow

Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein, Twin-Strep Tag&Tag Free

Cat. No. / Size
Price
Availability
Qty
IT1-H5283-100ug
$465.00
In Stock - Delivery in 1-2 business days
IT1-H5283-1mg (500ug X 2)
$3,370.00
In Stock - Delivery in 2 weeks
IT1-H5283
Sub-Total :
$ 0
Customize Product Request Quote
Contact Us
Contact Us
Sub-Total:
$ 0
Request Quote
Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

Integrin alpha 8 beta 1, ITGA8&ITGB1

Source

Human ITGA8&ITGB1 Heterodimer Protein, Twin-Strep Tag&Tag Free (IT1-H5283) is expressed from human 293 cells (HEK293). It contains AA Phe 39 - Leu 1012 (ITGA8) Gln 21 - Asp 728 (ITGB1) (Accession # P53708-1 (ITGA8) & P05556-1 (ITGB1)).

Predicted N-terminus: Phe 39 (ITGA8) Gln 21 (ITGB1)

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

Human ITGA8&ITGB1 Heterodimer Protein, Twin-Strep Tag&Tag Free, produced by co-expression of ITGA8 and ITGB1, has a calculated MW of 116.4 kDa (ITGA8) and 83.7 kDa (ITGB1). Subunit ITGA8 is fused with Twin-Strep tag at the C-terminus and subunit ITGB1 contains no tag. The protein migrates as 150-180 kDa (ITGA8) and 95-110 kDa (ITGB1) when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System

Background

Human Integrin alpha 8 beta 1 Heterodimer Protein consists of ITGA8 and ITGB1. The integrin alpha 8 subunit, isolated by low stringency hybridization, is a novel integrin subunit that associates with beta 1. The recently identified alpha 8 integrin subunit associates with beta 1 and is predominantly expressed in smooth muscle and other contractile cells in adult tissues, and in mesenchymal and neural cells during development. In addition, Integrin alpha 8 beta 1 is a receptor for fibronectin and can promote attachment, cell spreading, and neurite outgrowth on fibronectin.