Human Activin RIB & Activin RIIB Protein, Fc Tag&Fc Tag

Synonyms

ACTRIIB, ActR-IIB, HTX4

Source

Human Activin RIB & Activin RIIB Protein, Fc Tag&Fc Tag (ACB-H5253) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Glu 126 & Gly 20 - Pro 133 (Accession # P36896-1 & Q13705-1).

Molecular Characterization

Other Tags and Version Biotin & Other Labeled Version

Human Activin RIB & Activin RIIB Protein, Fc Tag&Fc Tag is produced by co-expression of Activin RIB and Activin RIIB, has a calculated MW of 37 kDa & 39.1 kDa. Subunit Activin RIB is fused with a human IgG1 Fc tag at the C-terminus and subunit Activin RIIB is fused with a human IgG1 Fc tag at the C-terminus. The protein migrates as 80-95 kDa and >150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>90% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.

ACRO Quality Management System

1. QMS(ISO, GMP)
2. Quality Advantages
3. Quality Control Process