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Anti-SARS-CoV-2 Spike S1 Antibody, Mouse IgG1 (AS58)

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S1N-S58A1-100ug
$450.00
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S1N-S58A1-1mg
$3,255.00
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S1N-S58A1
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Product Details
Performance Data
Reviews & Citations
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources

  • Source

    Anti-SARS-CoV-2 Spike S1 Antibody, Mouse IgG1 (AS58) (S1N-S58A1), originally from mouse immunized with recombinant SARS-CoV-2 Spike S1 protein, is produced from hybridoma.

  • Clone

    AS58

  • Species

    Mouse

  • Isotype

    Mouse IgG1 | Kappa

  • Conjugate

    Unconjugated

  • Antibody Type

    Hybridoma Monoclonal

  • Reactivity

    Virus

  • Specificity

    This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. No cross-reactivity is detected with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.

  • Application

    Application
    Recommended Usage
    ELISA
    0.1-10 ng/mL

  • Purity

    95% as determined by SDS-PAGE.

  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.