Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (AM334) (Beta & Gamma Specific) (MALS verified)

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SPD-M334-100ug
$925.00
SPD-M334-1mg
$6,255.00
SPD-M334
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  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
  • Source

    Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (AM334) (Beta & Gamma Specific) (SPD-M334) is a mouse monoclonal antibody recombinantly expressed from HEK293 cells. The antibody is specific against the Beta (B.1.351) and Gamma (P.1) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus, the Alpha (B.1.1.7) variant, the Delta (B.1.617.2) variant and the Omicron (B.1.1.529, BA.2) variant.

  • Clone

    AM334

  • Species

    Mouse

  • Isotype

    Mouse IgG1 | Mouse Kappa

  • Antibody Type

    Recombinant Monoclonal

  • Reactivity

    Virus

  • Immunogen

    Recombinant SARS-CoV-2 (COVID-19) S protein RBD (K417N, E484K, N501Y) erived from human 293 cells

  • Specificity

    This product is a specific antibody specifically reacts with SARS-CoV-2 (COVID-19) S protein RBD (K417N, E484K, N501Y) (Cat. No.SPD-C52Hp), Gamma (Cat. No. SPD-C52Hr), B.1.1.529/Omicron (Cat. No. SPD-C522e), BA.2/Omicron (Cat. No. SPD-C522g), BA.3/Omicron. No cross-reactivity is detected with Spike RBD of WT (Cat. No. SPD-C52H3), Alpha (Cat. No. SPD-C52Hn), Delta (Cat. No. SPD-C52Hh), BA.4&5Omicron (Cat. No. SPD-C522r), XBB/Omicron (Cat. No. SPD-C5241) and XBB.1.5/Omicron (Cat. No. SPD-C5242).

  • Application

    Application
    Recommended Usage
    ELISA
    0.06-5000 ng/mL
  • Purity

    95% as determined by SDS-PAGE.

    90% as determined by SEC-MALS.

  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 12 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.