COA
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Anti-SARS-CoV-2 Spike NTD Antibody, Human IgG1 is isolated from a Spike NTD infected Human and is recombinantly produced from human 293 cells (HEK293).
Human IgG1/kappa
This product is a specific antibody specifically reacts with Spike NTD.
ELISA
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Less than 1.0 EU per μg by the LAL method.
Supplied as 0.2 μm filtered solution in PBS, pH7.4.
Contact us for customized product form or formulation.
This product is supplied and shipped with dry ice, please inquire the shipping cost.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
S protein has two functional regions, S1 and S2. S1 is composed of four domains, including N-amino-terminal domain (NTD) and receptor-binding domain (RBD), and binds to host cell receptor ACE2. Compared with RBD antibody, the neutralization ability of NTD antibody is weak, most of which can recognize the three-dimensional conformation of viral protein. In the NTD region of mutant strains, there are a large number of amino acid deletion and insertion, as well as numerous point mutations, most of which can escape the recognition and neutralization of NTD antibody.