HRP conjugated Monoclonal Anti-MMAE&MMAF Antibody,Mouse IgG1

  • Antibody Internalization Detection Reagent (IGG-PZF2001) monitors endocytosis in live cells
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Cat. No. / Size
Price
Qty
MME-PLS104-25ug
$415.00
MME-PLS104-200ug
$1705.00
ETA of in-stock products:2 business days

Product Details

  • Source

    HRP conjugated Monoclonal Anti-MMAE&MMAF Antibody,Mouse IgG1 is a recombinant mouse monoclonal antibody expressed in HEK293 cells.

  • Antibody Type

    Recombinant Monoclonal

  • Isotype

    Mouse IgG1, Kappa

  • Immunogen

    MMAE

  • Conjugate

    HRP Labeled

  • Specificity

    Specifically recognizes the target-MMAE.

  • Application

    Application
    Recommended Usage
    ELISA
    1:300-1:3000
  • Purification

    Protein A purified / Protein G purified.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     MMAE ELISA

    Immobilized Disitamab Vedotin at 1 μg/mL (100 μL/well) can bind HRP conjugated Monoclonal Anti-MMAE&MMAF Antibody,Mouse IgG1 (Cat. No. MME-PLS104) with a linear range of 0.5-16 ng/mL (QC tested).

    Protocol
  •  MMAE ELISA

    Immobilized Human Her2, His Tag (Cat. No. HE2-H5225) at 1 μg/mL, add Disitamab Vedotin (RC48) in the 100% Human Serum and then add HRP conjugated Monoclonal Anti-MMAE&MMAF Antibody,Mouse IgG1 (Cat. No. MME-PLS104) at 0.5 μg/mL (QC tested).

    Protocol
  •  MMAE ELISA

    Immobilized Human Her2, His Tag (Cat. No. HE2-H5225) at 1 μg/mL, add Disitamab Vedotin (RC48) in the 0.5% BSA and then add HRP conjugated Monoclonal Anti-MMAE&MMAF Antibody,Mouse IgG1 (Cat. No. MME-PLS104) at 0.5 μg/mL (Routinely tested).

    Protocol

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Background

Monomethyl auristatin E (MMAE) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. Anti-MMAE antibody is a Mouse monoclonal antibody. HRP-anti-MMAE antibody is the conjugation of HRP and anti-MMAE antibody. This antibody has been shown to work in applications such as: PK, PD, Immunoassay and ELISA.

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