HRP conjugated Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1G11)

  • Antibody Internalization Detection Reagent (IGG-PZF2001) monitors endocytosis in live cells
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Cat. No. / Size
Price
Qty
ERN-PLM12b-25ug
$470.00
ERN-PLM12b-200ug
$1845.00
ETA of in-stock products:2 business days

Product Details

  • Source

    HRP conjugated Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1G11) is a rabbit monoclonal antibody recombinantly expressed in HEK293 cells.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    1M1G11

  • Isotype

    Rabbit IgG, Kappa

  • Conjugate

    HRP Labeled

  • Specificity

    This product is a specific antibody specifically reacts with Eribulin.

  • Purification

    Protein A purified / Protein G purified.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     Eribulin ELISA

    Immobilized Human FOLR1, Fc Tag (Cat. No. FO1-H5253) at 1 μg/mL, add Farletuzumab Ecteribulin in the 100% Human Serum and then add HRP conjugated Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1G11) (Cat. No. ERN-PLM12b) at 0.05 μg/mL (QC tested).

    Protocol
  •  Eribulin ELISA

    Immobilized Farletuzumab Ecteribulin at 1 μg/mL (100 μL/well) can bind HRP conjugated Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1G11) (Cat. No. ERN-PLM12b) with a linear range of 0.5-16 ng/mL (Routinely tested).

    Protocol

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Background

Eribulin is a synthetic analogue of the macrocyclic polyether halichondrin B, which was originally isolated from the Asian sea sponge Halichondria okadai. Eribulin binds specifically to the β-tubulin subunit on the (+) end of the microtubule and potently inhibits elongation of the formed microtubule, while having little or no effect on microtubule depolymerization. Eribulin's potent antimitotic activity and nonmitotic effects on tumor biology make it an interesting candidate for investigation as a MTA payload for ADCs.

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