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Product Details
Source
Biotinylated Anti-Human CD3 Antibody, Mouse F(ab')2, His,Avitag (Clone: OKT3), premium grade (CDE-CV81G0) is an F(ab')2 fragment-only antibody recombinantly expressed from HEK293 cells.
It is produced under our rigorous quality control system that incorporates a comprehensive set of tests including sterility and endotoxin tests. Product performance is carefully validated and tested for compatibility for cell culture use or any other applications in the early preclinical stage. When ready to transition into later clinical phases, we also offer a custom GMP protein service that tailors to your needs. We will work with you to customize and develop a GMP-grade product in accordance with your requests that also meets the requirements for raw and ancillary materials use in cell manufacturing of cell-based therapies.
Conjugate
Biotin
Specificity
This product is a specific antibody specifically reacts with CD3 epsilon.
Endotoxin
Less than 0.002 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
>95% as determined by SEC-HPLC.
Sterility
Negative
Mycoplasma
Negative
Formulation
Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Shipping
This product is supplied and shipped with dry ice, please inquire the shipping cost.
Storage
For long term storage, the product should be stored at liquid state at -70°C.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -70°C for 12 months.
ACRO Quality Management System
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Performance Data
SDS-PAGE
Biotinylated Anti-Human CD3 Antibody, Mouse F(ab')2, His,Avitag (Clone: OKT3), premium grade on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).
SEC-HPLC
The purity of Biotinylated Anti-Human CD3 Antibody, Mouse F(ab')2, His,Avitag (Clone: OKT3), premium grade (Cat. No. CDE-CV81G0) was greater than 95% as determined by SEC-HPLC.
Bioactivity-FACS
Flow cytometric analysis of Human peripheral blood lymphocytes respectively staining Biotinylated Anti-Human CD3 Antibody, Mouse F(ab')2, His,Avitag (Clone: OKT3), premium grade (Cat. No. CDE-CV81G0) at 0.1 µg/mL (0.01 µg corresponds to labeling of 1e6 cells in a final volume of 100 µL) and PE Streptavidin. PE signal was used to evaluate the binding activity (QC tested).
Protocol
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Background
Recent Advances
Drug Development Progress- English Name：
T cell surface glycoprotein CD3
- Category：
- Approved Drugs：
10 Details
- Drugs in Clinical Trials：
198 Details
- Highest Development Stage：
Approved
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