Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3), premium grade (CHO)

• Seamless Transition from Preclinical to Clinical: Same cell clone, process, and QC as GMP products.
• Enhanced Production Standards: AOF raw materials, pharma-grade excipients, Grade B+A (ISO 5) environment.
• Comprehensive Quality Control: Additional strict testing for process impurities, sterility, and mycoplasma.
• Cost-Effective Solution: GMP-comparable quality at an economical price for early development.
• Risk Mitigation: Enhanced safety through rigorous impurity control and comprehensive testing.

Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3), premium grade (CDE-CH44G1) is recombinantly produced from CHO cells.

It is produced under our rigorous quality control system that incorporates a comprehensive set of tests including sterility and endotoxin tests. Product performance is carefully validated and tested for compatibility for cell culture use or any other applications in the early preclinical stage. When ready to transition into later clinical phases, we also offer a custom GMP protein service that tailors to your needs. We will work with you to customize and develop a GMP-grade product in accordance with your requests that also meets the requirements for raw and ancillary materials use in cell manufacturing of cell-based therapies.

Mouse IgG2a, Kappa

This product is a specific antibody specifically reacts with CD3 epsilon.

Less than 0.002 EU per μg by the LAL method / rFC method.

<5 ppm of protein tested by ELISA.

<0.5 ng/μg of protein tested by ELISA.

<0.02 ng/μg of protein tested by qPCR.

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

Negative

Negative

Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

This product is supplied and shipped with dry ice, please inquire the shipping cost.

For long term storage, the product should be stored at liquid state at -70°C.

Please avoid repeated freeze-thaw cycles.

• 2-8°C for 12 months under sterile conditions;
• -70°C for 24 months.

ACRO's Research-grade products are suitable for a wide range of cell culture applications, particularly for research use in academic institutions. These products are sterilized by filtration, followed by lyophilization where applicable. Typical specifications include endotoxin levels of <0.01 EU/μg and purities >95%. Biological activity is calibrated against WHO/NIBSC standards when available.
ACRO's Premium-grade (Pre-GMP) products are characterized by their high quality and enhanced safety profiles, making them ideal for early-stage discovery and manufacturing processes in cell therapy companies. A key advantage is their seamless transition to corresponding GMP-grade versions. Biological activity is calibrated against WHO/NIBSC standards when available. Typical specifications include endotoxin levels of <0.01 EU/μg and purities >95%. In addition, rigorous testing is conducted to ensure the absence of mycoplasma, HCD, and HCP, thereby guaranteeing product safety.