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Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Ensereptide | PXL-01 | Phase 3 Clinical | Promore Pharma | Post-surgical adhesions; Tissue Adhesions; Cicatrix | Details |
| Efprezimod alfa | CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110 | Phase 3 Clinical | Oncoimmune Inc | Solid tumours; Hematopoietic stem cell transplantation (HSCT); Leukemia; HIV Infections; Graft vs Host Disease; Myelodysplastic Syndromes; Coronavirus Disease 2019 (COVID-19); Precursor Cell Lymphoblastic Leukemia-Lymphoma; Dyslipidemias; Leukemia, Myeloid, Acute; Melanoma | Details |
| Lutikizumab | ABT-981 | Phase 3 Clinical | Abbvie Inc | Colitis, Ulcerative; Osteoarthritis, Knee; Hidradenitis Suppurativa; Osteoarthritis; Crohn Disease; Dermatitis, Atopic | Details |
| Goflikicept | RPH-104 | Phase 3 Clinical | Trpharm | Familial Mediterranean Fever; Still's Disease, Adult-Onset; Schnitzler Syndrome; ST Elevation Myocardial Infarction; Pancreatitis; Coronavirus Disease 2019 (COVID-19); Pericarditis; Arthritis, Gouty; Gout | Details |
| Recombinant humanized monoclonal antibody antiIL-1β(Cp Guojian) | SSGJ-613 | Phase 3 Clinical | Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd | Tumor necrosis factor receptor associated periodic syndrome; Arthritis, Juvenile; Arthritis, Gouty; Gout; Inflammation | Details |
| MAS-825 | MAS-825; MAS825 | Phase 3 Clinical | Novartis Pharmaceuticals Corp | Enterocolitis; Coronavirus Disease 2019 (COVID-19); Coronary Disease; Autoimmune Lymphoproliferative Syndrome | Details |
| CU-06 | CU-06-EYE; CU-06-IBD; CU-061004; Sac-1004; CU-06-ONCO; CU-06-HAE; CU06-1004 | Phase 2 Clinical | Curacle Co Ltd | Myocardial Infarction; Neoplasms; Lung Diseases; Stroke; Diabetic macular oedema; Colitis, Ulcerative; Crohn Disease; Macular Degeneration; Angioedemas, Hereditary; Diabetic Retinopathy | Details |
| IL1-beta receptor antagonist Therapy(Hamlet BioPharma) | Phase 2 Clinical | Hamlet BioPharma AB | Cystitis; Pain | Details | |
| Diacerein (TWi Biotechnology/Castle Creek Pharmaceuticals) | AC-201; AC-201 Controlled release tablet; AC-201 CR; AC-203; CCP 020; CCP-020 | Phase 2 Clinical | Twi Biotechnology Inc | Diabetes Mellitus, Type 2; Epidermolysis Bullosa; Epidermolysis Bullosa Simplex; Pemphigoid, Bullous; Epidermolysis Bullosa, Junctional; Arthritis; Gout; Epidermolysis Bullosa Dystrophica | Details |
| Gevokizumab | XMA-005.2; AB-7; XOMA-052; S-78989; VPM-087; XMA-0052 | Phase 1 Clinical | Xoma Corp | Colonic Neoplasms; Behcet Syndrome; Labyrinth Diseases; Panuveitis; Osteoarthritis; Uveitis; Colorectal Neoplasms; Cryopyrin-Associated Periodic Syndromes; Arthritis, Rheumatoid; Acne Vulgaris; Hereditary Autoinflammatory Diseases; Stomach Neoplasms; Esophageal Neoplasms; Carcinoma, Renal Cell; Pyoderma Gangrenosum; Diabetes Mellitus, Type 2; Diabetes Mellitus, Type 1 | Details |
| DLX-2323 | DLX-2323 | Phase 1 Clinical | Delenex Therapeutics Ag | Inflammation | Details |
| Tavo-103 | Tavo103; Tavo-103; TAVO-103A; TAVO103A | Phase 1 Clinical | Tavotek Biotherapeutics (Hong Kong) Ltd | Details | |
| FL-101 | FL-101 | Phase 1 Clinical | Flame Biosciences Inc | Urinary Bladder Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| AK-114 | AK-114; AK114 | Phase 1 Clinical | Zhongshan Akeso Biopharma Co Ltd | Solid tumours; Neoplasms; Inflammation; Neoplasm Metastasis | Details |
Marketed Drug Information
| English Name | Research Code | Highest Development Stage | Company | Earliest Brand Name | Earliest Approval Country | Earliest Indication | Earliest Approval Company | Earliest Approval Date | Indication | Clinical Trial |
|---|---|---|---|---|---|---|---|---|---|---|
| Canakinumab | ACZ-885 | Approved | Novartis Pharma Ag | Ilaris | United States | Muckle-Wells Syndrome (MWS); Cryopyrin-Associated Periodic Syndromes | Novartis Pharma Ag | 2009-06-17 | Gout; Hyperimmunoglobulin D syndrome; Dry Eye Syndromes; Arthritis, Gouty; Cryopyrin-Associated Periodic Syndromes; Wet Macular Degeneration; Sarcoidosis, Pulmonary; Cognitive Dysfunction; Alzheimer Disease; Primary Myelofibrosis; Muscular Dystrophy, Duchenne; Urticaria; Mucocutaneous Lymph Node Syndrome; Pulmonary Disease, Chronic Obstructive; Lung Neoplasms; Diabetes Mellitus; Carcinoma, Non-Small-Cell Lung; Anemia, Sickle Cell; Thrombocythemia, Essential; Diabetic Retinopathy; Peripheral Arterial Disease; Aortic Aneurysm, Abdominal; Behcet Syndrome; Polyarticular Juvenile Idiopathic Arthritis; Hepatitis, Alcoholic; Diabetes Mellitus, Type 1; Prediabetic State; Familial Mediterranean Fever; Mevalonate Kinase Deficiency; Anemia; Atherosclerosis; Schnitzler Syndrome; Polycythemia Vera; Diabetes Mellitus, Type 2; Still's Disease, Adult-Onset; Pyoderma Gangrenosum; Myelodysplastic Syndromes; Arthritis, Rheumatoid; Coronavirus Disease 2019 (COVID-19); Vasculitis; Hereditary Autoinflammatory Diseases; Muckle-Well | Details |
| PG-201 | PG-201 | Approved | Viromed | Layla | South Korea | Osteoarthritis | Pmg Pharm Co Ltd | 2012-01-01 | Osteoarthritis, Knee; Osteoarthritis | Details |
| Edaravone/(+)-2-Decanol | SIM-071201 | Approved | Jiangsu Simcere Pharmaceutical Co Ltd | 三贝心, 三贝欣, 先必新, Sanbexin | Mainland China | Stroke | Nanjing Simcere Dongyuan Pharmaceutical Co Ltd | 2020-07-29 | Brain Infarction; Cerebral Hemorrhage; Stroke; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Cognition Disorders | Details |
| Diacerein | KW-4800; SF-277; Art-50 | Approved | Cartivix, Fisiodar, Verboril, Art, 安必丁, Artrodar, Artrolyt | Metabolic Dysfunction-Associated Steatotic Liver Disease; Diabetes Mellitus, Type 2; Insulin Resistance; Coronavirus Disease 2019 (COVID-19); Epidermolysis Bullosa; Osteoarthritis, Knee; Diabetes Complications; Osteoarthritis; Obesity; Osteoarthritis, Hip; Diabetes Mellitus; Overweight | Details | |||||
| Andrographolide/Sodium Hydrogen Sulfite | Approved | Bacterial Infections | Details | |||||||
| Edaravone/(+)-2-Decanol (Yantai Yene/Simcere) | Y-2 | Approved | Yantai Yene Pharma Co Ltd, Simcere Pharmaceutical Group Ltd, Beijing Tiantan Hospital, Capital Medical University | Mainland China | Stroke | Jiangsu Simcere Pharmaceutical Co Ltd | 2024-12-01 | Intracranial Hemorrhages; Stroke; Cognitive Dysfunction | Details | |
| Rilonacept | RGN-303; KPL-914 | Approved | Arcalyst, 炎朵 | United States | Cryopyrin-Associated Periodic Syndromes | Kiniksa Pharmaceuticals Ltd | 2008-02-27 | Pericarditis; Inflammation; Scleroderma, Diffuse; Renal Insufficiency, Chronic; Gout; Urticaria; Vascular Diseases; Cardiomyopathies; Cryopyrin-Associated Periodic Syndromes; Hearing Loss, Sensorineural; Genetic Diseases, Inborn; Diabetes Mellitus, Type 1; Arthritis, Juvenile; Coronary Artery Disease; Deficiency of interleukin-1 receptor antagonist; Scleroderma, Systemic; Muckle-Wells Syndrome (MWS); Atherosclerosis; Schnitzler Syndrome; Anemia; Still's Disease, Adult-Onset; Familial Mediterranean Fever | Details | |
| Thalidomide | NSC-66847; NSC-527179; K-17; VP-02; FPF-300; FPF300 | Approved | Celgene Corp | Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled | Mainland China | Leprosy, Lepromatous; Multiple Myeloma | Changzhou Pharmaceutical Factory | 1982-01-01 | HIV Wasting Syndrome; Angiodysplasia; Primary Myelofibrosis; Neuroectodermal Tumors, Primitive; Prostatitis; Colorectal Neoplasms; Osteosarcoma; Lymphoma, Mantle-Cell; Sarcoma, Ewing; Retinoblastoma; Erythema Nodosum; Drug Resistant Epilepsy; Xerostomia; Sarcoma; Pancreatitis, Chronic; Adenocarcinoma, Clear Cell; Lymphoma, Follicular; Arachnoiditis; Carcinoma, Adenosquamous; Gastrointestinal Hemorrhage; Cholangitis, Sclerosing; Prostatic Neoplasms; Pelvic Pain; Neoplasm Metastasis; Stomatitis; Burning Mouth Syndrome; Mycobacterium avium-intracellulare Infection; Amyotrophic Lateral Sclerosis; Melanoma; Myelodysplastic-Myeloproliferative Diseases; Carcinoma, Hepatocellular; Leukemia, Lymphocytic, Chronic, B-Cell; Vascular Malformations; Tuberculosis; Appendiceal Neoplasms; Lymphoma, Non-Hodgkin; Uterine Neoplasms; Anemia, Sideroblastic; Glioma; Leprosy, Lepromatous; Endometrial Neoplasms; Lung Neoplasms; Waldenstrom Macroglobulinemia; Kidney Neoplasms; Thalassemia; Carcinoid Tumor; Lupus Erythematosus, Discoid | Details |
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